PMID: Dermatol Online J. 2018 Nov 15 ;24(11). Epub 2018 Nov 15. PMID: 30695972 Abstract Title: A systematic review on the use of cryotherapy versus other treatments for basal cell carcinoma. Abstract: BACKGROUND: Cryotherapy is a commonly discussed method for treatment of basal cell carcinoma skin cancer. Some uncertainty remains about its efficacy relative to …
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Oral cryotherapy is a tolerable and cost-effective method of diminishing oral thermal hyperalgesia in patients receiving oxaliplatin chemotherapy.
PMID: J Natl Compr Canc Netw. 2019 Apr 1 ;17(4):358-364. PMID: 30959472 Abstract Title: Efficacy of Oral Cryotherapy During Oxaliplatin Infusion in Preventing Oral Thermal Hyperalgesia: A Randomized Trial. Abstract: BACKGROUND: Chemotherapy-induced oral thermal hyperalgesia (OTH) is a common and debilitating side effect of platinum-based anticancer agents. This study evaluated the efficacy of oral cryotherapy …
Almost all neonatal ergot toxicity has involved confusion of maternal methylergonovine with neonatal vitamin K.
PMID: Am J Perinatol. 2005 Jul ;22(5):239-43. PMID: 16041632 Abstract Title: Neonatal ergot poisoning: a persistent iatrogenic illness. Abstract: Ergot toxicity in the newborn usually manifests itself as respiratory depression, cyanosis, oliguria, and seizures. Death is usually caused by respiratory failure. A limited number of neonatal cases have been reported worldwide, and almost all cases …
A clinical trial is needed to establish the risk benefit ratio of vitamin K injections for infants at low risk of haemorrhagic diseases.
PMID: BMJ. 1994 Apr 2 ;308(6933):908-10. PMID: 8173376 Abstract Title: Why we need a clinical trial for vitamin K. Abstract: Vitamin K is given to many babies born in the United Kingdom, but we still do not know if it has substantial hazards. Because the population exposed to vitamin K is very large even quite …
Oral cryotherapy was effective for reducing oral mucositis, reactive oxygen series, and inflammatory cytokines in patients undergoing chemotherapy.
PMID: J Korean Acad Nurs. 2019 Apr ;49(2):149-160. PMID: 31064968 Abstract Title: [The Effects of Oral Cryotherapy on Oral Mucositis, Reactive Oxygen Series, Inflammatory Cytokines, and Oral Comfort in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial]. Abstract: PURPOSE: The purpose of this study was to examine the effects of oral cryotherapy on oral …
A case series of 12 newborns with ergot poisoning as a result of accidental administration of methylergonovine instead of vitamin K injections.
PMID: Eur J Pediatr. 2011 May ;170(5):633-7. Epub 2010 Oct 23. PMID: 20972685 Abstract Title: An unusual mimicker of a sepsis outbreak: ergot intoxication. Abstract: Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country …
A case series of newborn medication-dispensing errors involving vaccines and vitamin K injections.
PMID: Am J Health Syst Pharm. 2010 Jan 1 ;67(1):49-57. PMID: 20044369 Abstract Title: Origins of and solutions for neonatal medication-dispensing errors. Abstract: PURPOSE: Five cases of sound-alike, look-alike, neonatal medication-dispensing errors and their resolution are reviewed.SUMMARY: In 2008, there were five cases in which look-alike or sound-alike neonatal medication-dispensing errors occurred at our institution. …
A risk of acute lymphatic leukemia associated with vitamin K injections cannot be ruled out, however, its oral counterpart is likely as effective without the carcinogenic effect.
PMID: Drug Saf. 1999 Jul ;21(1):1-6. PMID: 10433349 Abstract Title: Oral versus intramuscular phytomenadione: safety and efficacy compared. Abstract: Oral and intramuscular phytomenadione (vitamin K1) prophylaxis became an issue following the report of a potential carcinogenic effect of intramuscular but not oral phytomenadione prophylaxis. There is increasing evidence, however, that oral phytomenadione prophylaxis is less …
Low vitamin K in fetuses may be a protective measure against xenobiotic entry via the placenta.
PMID: Semin Thromb Hemost. 1995 ;21(4):357-63. PMID: 8747698 Abstract Title: Observations on vitamin K deficiency in the fetus and newborn: has nature made a mistake? Abstract: The microsomal mixed function oxidase system metabolizes xenobiotics (Phase I) to products that, if not activated and conjugated for excretion (Phase II), are capable of forming conjugates with cellular …
A case report of an accidental substitution of vitamin K injection with ephedrine.
PMID: Ugeskr Laeger. 2001 Sep 24 ;163(39):5365-7. PMID: 11590951 Abstract Title: [Risk management by reporting critical incidents. Vitamin K and ephedrine mix-up at a birthing unit]. Abstract: INTRODUCTION: Errors of medication are frequent causes of hazards to patients. It has been suggested that containers that look alike constitute a risk of such errors. In this …
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