Cryotherapy helps to prevent paclitaxel induced peripheral neuropathy.

PMID:  Breast. 2019 Dec ;48:89-97. Epub 2019 Sep 19. PMID: 31590108 Abstract Title:  Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial. Abstract:  PURPOSE: This pilot trial aimed to assess if cooling hands and feet with crushed ice during receipt of paclitaxel helps prevent peripheral neuropathy.METHODS: This prospective, randomized trial …

A pilot trial of pembrolizumab plus prostatic cryotherapy for men with newly diagnosed oligometastatic hormone-sensitive prostate cancer.

PMID:  Prostate Cancer Prostatic Dis. 2019 Oct 14. Epub 2019 Oct 14. PMID: 31611635 Abstract Title:  A pilot trial of pembrolizumab plus prostatic cryotherapy for men with newly diagnosed oligometastatic hormone-sensitive prostate cancer. Abstract:  BACKGROUND: Monotherapy with immune checkpoint inhibitors has generally been unsuccessful in men with advanced prostate cancer. Preclinical data support the notion …

Beneficial effects of cryotherapy on chemotherapy-induced peripheral neuropathy.

PMID:  Nihon Yakurigaku Zasshi. 2019 ;154(5):245-248. PMID: 31735752 Abstract Title:  [Effects of cryotherapy on chemotherapy-induced peripheral neuropathy: self-controlled clinical trial]. Abstract:  Chemotherapy induced peripheral neuropathy (CIPN) is a numbness or tingling of the hands and feet that occur as a side effect of anticancer drugs including taxanes and platinum drugs. The effective treatments or preventive …

Cryotherapy is a method with a high success rate in healing of genital warts.

PMID:  Mater Sociomed. 2019 Sep ;31(3):212-214. PMID: 31762705 Abstract Title:  Cryotherapy of Genital Warts. Abstract:  Introduction: Genital warts are a frequent form of sexually transmitted disease. Cryotherapy represents the first line of therapy. Healing occurs in 94%, and recurrence in 10% . Side effects are common during the treatment.Aim: The aim of this study is …

Improved antioxidative protection in winter swimmers

PMID:  QJM. 1999 Apr ;92(4):193-8. PMID: 10396606 Abstract Title:  Improved antioxidative protection in winter swimmers. Abstract:  Adaptation to oxidative stress is an improved ability to resist the damaging effects of reactive oxygen species, resulting from pre-exposure to a lower dose. Changes in uric acid and glutathione levels during ice-bathing suggest that the intensive voluntary short-term …

The effectiveness of the whole body cryotherapy strategies.

PMID:  Biomed Res Int. 2019 ;2019:2065346. Epub 2019 May 15. PMID: 31223612 Abstract Title:  The Effectiveness of the Whole Body Cryotherapy Strategies: A Comparison of Different Duration and Temperature on the Antioxidative Status in the Experimental Rat Model. Abstract:  Background: We examined the effectiveness of the systemic cryotherapy in terms of the temperature and duration …

Changes in the glutathione system of erythrocytes due to enhanced formation of oxygen free radicals during short-term whole body cold stimulus.

PMID:  Arctic Med Res. 1992 Jan ;51(1):3-9. PMID: 1562293 Abstract Title:  Changes in the glutathione system of erythrocytes due to enhanced formation of oxygen free radicals during short-term whole body cold stimulus. Abstract:  The red cell glutathione levels of 10 healthy volunteers who are accustomed to winter-swimming were measured before and after this short-term whole …

Uric acid and glutathione levels are increased during short-term whole body cold exposure.

PMID:  Free Radic Biol Med. 1994 Mar ;16(3):299-305. PMID: 8063192 Abstract Title:  Uric acid and glutathione levels during short-term whole body cold exposure. Abstract:  Ten healthy subjects who swim regularly in ice-cold water during the winter (winter swimming), were evaluated before and after this short-term whole body exposure. A drastic decrease in plasma uric acid …

Psychedelic drugs-a new era in 
psychiatry?


PMID:  Dialogues Clin Neurosci. 2019 ;21(2):139-147. PMID: 31636488 Abstract Title:  Psychedelic drugs-a new era in
psychiatry?
. Abstract:  This article covers the renaissance of classical psychedelic drugs such as psilocybin and LSD plus 3,4-methylene dioxymethamphetamine (MDMA-ecstasy) in psychiatric research. These drugs were used quite extensively before they became prohibited. This ban had little impact on recreational use, …

Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in ‘magic’ mushrooms.

PMID:  Chemistry. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31729089 Abstract Title:  Simultaneous Production of Psilocybin and a Cocktail ofβ-Carboline Monoamine Oxidase Inhibitors in 'Magic' Mushrooms. Abstract:  The psychotropic effects of Psilocybe"magic"mushrooms are caused by the L-tryptophan-derived alkaloid psilocybin. Despite their significance, the secondary metabolome of these fungi is poorly understood in general. Our …

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