PMID: Pharm Biol. 2017 Dec ;55(1):1149-1154. PMID: 28219252 Abstract Title: A phlorotannin constituent of Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice. Abstract: CONTEXT: 2,7″-Phloroglucinol-6,6'-bieckol is a type of phlorotannin isolated from brown algae, Ecklonia cava Kjellman (Phaeophyceae; Laminareaceae). 2,7″-Phloroglucinol-6,6'-bieckol mediates antioxidant activities. However, there has been no research on improving postprandial hyperglycaemia using 2,7″-phloroglucinol-6,6'-bieckol.OBJECTIVE: …
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Ameliorative effect of Ecklonia cava polyphenol extract on renal inflammation.
PMID: J Agric Food Chem. 2017 May 17 ;65(19):3811-3818. Epub 2017 May 5. PMID: 28459555 Abstract Title: Ameliorative Effect of Ecklonia cava Polyphenol Extract on Renal Inflammation Associated with Aberrant Energy Metabolism and Oxidative Stress in High Fat Diet-Induced Obese Mice. Abstract: Immoderate fat accumulation causes both oxidative stress and inflammation, which can induce kidney …
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Crude Ecklonia cava flake extracts may be a potential treatment against exogenous pathogen-mediated inflammation.
PMID: Molecules. 2017 May 10 ;22(5). Epub 2017 May 10. PMID: 28489052 Abstract Title: Crude Ecklonia cava Flake Extracts Attenuate Inflammation through the Regulation of TLR4 Signaling Pathway in LPS-Induced RAW264.7 Cells. Abstract: We investigated the beneficial effects of the crudeflake (CEF), which is a residual product after polyphenol extraction from, on inflammation in LPS-stimulated …
Cardioprotective effects of a phlorotannin extract against doxorubicin-induced cardiotoxicity.
PMID: J Med Food. 2017 Oct ;20(10):944-950. Epub 2017 Aug 17. PMID: 28816580 Abstract Title: Cardioprotective Effects of a Phlorotannin Extract Against Doxorubicin-Induced Cardiotoxicity in a Rat Model. Abstract: Long-term therapy with doxorubicin (DOX) is associated with high incidence of cumulative and irreversible dilated cardiomyopathy. The goal of this study was to evaluate the cardioprotective …
Inhibitory activity of minor phlorotannins from Ecklonia cava on α-glucosidase.
PMID: Food Chem. 2018 Aug 15 ;257:128-134. Epub 2018 Mar 6. PMID: 29622188 Abstract Title: Inhibitory activity of minor phlorotannins from Ecklonia cava onα-glucosidase. Abstract: α-Glucosidase is an enzyme that plays a key role in raising blood sugar level and is considered a good target for developing drugs to treat type 2 diabetes. This study …
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Ecklonia cava extract containing dieckol suppresses RANKL-induced osteoclastogenesis.
PMID: J Microbiol Biotechnol. 2019 Jan 28 ;29(1):11-20. PMID: 30518021 Abstract Title: Extract Containing Dieckol Suppresses RANKL-Induced Osteoclastogenesis via MAP Kinase/NF-κB Pathway Inhibition and Heme Oxygenase-1 Induction. Abstract: , an edible marine brown alga (Laminariaceae), is a rich source of bioactive compounds such as fucoidan and phlorotannins.extract (ECE) was prepared using 70% ethanol extraction and …
Therapeutic effect of Ecklonia cava extract in letrozole-induced polycystic ovary syndrome.
PMID: Front Pharmacol. 2018 ;9:1325. Epub 2018 Nov 19. PMID: 30524282 Abstract Title: Therapeutic Effect ofExtract in Letrozole-Induced Polycystic Ovary Syndrome Rats. Abstract: Polycystic ovary syndrome (PCOS) is an endocrinal disorder that afflicts mainly women of childbearing age. The symptoms of PCOS are irregular menstrual cycles, weight gain, subfertility and infertility. However, because the etiology …
Anti-neuroinflammatory property of phlorotannins from Ecklonia cava on Aβ25-35-induced damage in PC12 cells.
PMID: Mar Drugs. 2018 Dec 22 ;17(1). Epub 2018 Dec 22. PMID: 30583515 Abstract Title: Anti-Neuroinflammatory Property of Phlorotannins fromon Aβ-Induced Damage in PC12 Cells. Abstract: Alzheimer disease (AD) is a neurodegenerative disorder characterized by excessive accumulation of amyloid-beta peptide (Aβ) and progressive loss of neurons. Therefore, the inhibition of Aβ-induced neurotoxicity is a potential …
Ecklonia cava ethanol extract has potential therapeutic effects for the alleviation of periodontal disease.
PMID: Nutrients. 2019 May 22 ;11(5). Epub 2019 May 22. PMID: 31121899 Abstract Title: Anti-Inflammatory Effect ofExtract onLipopolysaccharide-Stimulated Macrophages and a Periodontitis Rat Model. Abstract: , an edible marine brown alga (Laminariaceae), is a rich source of phlorotannins. This study aimed to investigate the anti-inflammatory effect ofethanol extract (ECE, dieckol 10.6%,/) onlipopolysaccharide-stimulated inflammation in RAW …
Brown seaweed extract attenuates endothelial cell dysfunction.
PMID: Nutrients. 2019 Nov 15 ;11(11). Epub 2019 Nov 15. PMID: 31731817 Abstract Title: Extract Attenuates Endothelial Cell Dysfunction by Modulation of Inflammation and Brown Adipocyte Function in Perivascular Fat Tissue. Abstract: It is well known that perivascular fat tissue (PVAT) dysfunction can induce endothelial cell (EC) dysfunction, an event which is related with various …
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