PMID: Braz J Med Biol Res. 2019 Feb 14 ;52(2):e7843. Epub 2019 Feb 14. PMID: 30785478 Abstract Title: Kaempferol suppresses human gastric cancer SNU-216 cell proliferation, promotes cell autophagy, but has no influence on cell apoptosis. Abstract: Gastric cancer remains a serious threat to human health worldwide. Kaempferol is a plant-derived flavonoid compound with a …
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Protective effects of kaempferol on lipopolysaccharide-induced mastitis in mice.
PMID: Inflammation. 2014 Oct ;37(5):1453-8. PMID: 24743918 Abstract Title: Protective effects of kaempferol on lipopolysaccharide-induced mastitis in mice. Abstract: Kaempferol isolated from the root of Zingiberaceae plants galangal and other Chinese herbal medicines have been reported to have anti-inflammatory properties. However, the anti-inflammatory effects of kaempferol on lipopolysaccharide (LPS)-induced mastitis are unknown and their underlying …
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Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia.
PMID: Pharmacol Rep. 2017 Oct ;69(5):1113-1119. Epub 2017 May 13. PMID: 29031689 Abstract Title: Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia. Abstract: BACKGROUND: Postmenopausal osteoporosis and osteoporotic fractures constitute an increasing problem in developing countries. Kaempferol, isolated from seeds of Cuscuta chinensis, is an active flavonoid inhibiting in vitro …
Kaempferol induces apoptosis in HepG2 cells via activation of the endoplasmic reticulum stress pathway.
PMID: Mol Med Rep. 2016 Mar ;13(3):2791-800. Epub 2016 Feb 2. PMID: 26847723 Abstract Title: Kaempferol induces apoptosis in HepG2 cells via activation of the endoplasmic reticulum stress pathway. Abstract: Kaempferol is a flavonoid compound that has gained importance due to its antitumor properties; however, the underlying mechanisms remain to be fully understood. The present …
Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review.
PMID: Phytother Res. 2019 Feb ;33(2):263-275. Epub 2018 Nov 7. PMID: 30402931 Abstract Title: Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review. Abstract: Kaempferol, a natural flavonoid present in several plants, possesses a wide range of therapeutic properties such as antioxidant, anticancer, and anti-inflammatory. It has a significant role in reducing …
Kaempferol-induces vasorelaxation via endothelium-independent pathways in rat isolated pulmonary artery.
PMID: Pharmacol Rep. 2018 Oct ;70(5):863-874. Epub 2018 Mar 26. PMID: 30092416 Abstract Title: Kaempferol-induces vasorelaxation via endothelium-independent pathways in rat isolated pulmonary artery. Abstract: BACKGROUND: Kaempferol, a flavonoid, is the essential part of human diet. Flavonoids have different pharmacological activities like cardioprotective, anti-inflammatory and anti-oxidant. The aim of current study was to investigate vasorelaxant …
Kaempferol attenuates cardiac hypertrophy.
PMID: Planta Med. 2017 Jul ;83(10):837-845. Epub 2017 Feb 20. PMID: 28219095 Abstract Title: Kaempferol Attenuates Cardiac Hypertrophy via Regulation of ASK1/MAPK Signaling Pathway and Oxidative Stress. Abstract: Kaempferol has been demonstrated to provide benefits for the treatment of atherosclerosis, coronary heart disease, hyperlipidemia, and diabetes through its antioxidant and anti-inflammatory properties. However, its role …
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The present data demonstrated that Portulaca oleracea potentiates sleeping behaviors.
PMID: Curr Drug Discov Technol. 2019 ;16(2):198-203. PMID: 29521239 Abstract Title: Hypnotic Effect of Portulaca oleracea on Pentobarbital-Induced Sleep in Mice. Abstract: OBJECTIVE: In Iranian Traditional Medicine, the herbs with cold and wet temperament can help to improve insomnia. Portulaca oleracea has a cold and wet temperament, so the present study was carried out to …
HM-chromanone could be useful for the protection of pancreatic β-cells against oxidative stress and apoptosis induced by high glucose.
PMID: Nutrients. 2019 Feb 14 ;11(2). Epub 2019 Feb 14. PMID: 30769910 Abstract Title: HM-Chromanone Isolated fromL. Protects INS-1 Pancreaticβ Cells against Glucotoxicity-Induced Apoptosis. Abstract: In this study, we investigated whether ()-5-hydroxy-7-methoxy-3-(2'-hydroxybenzyl)-4-chromanone, a homoisoflavonoid compound isolated fromL., protects INS-1 pancreaticβ cells against glucotoxicity-induced apoptosis. Treatment with high glucose (30 mM) induced apoptosis in INS-1 pancreatic …
The antinociceptive effects of Portulaca oleracea might be due to antioxidant and anti-inflammatory properties.
PMID: CNS Neurol Disord Drug Targets. 2019 ;18(4):342-349. PMID: 30868971 Abstract Title: Attenuating Effect of Portulaca oleracea Extract on Chronic Constriction Injury Induced Neuropathic Pain in Rats: An Evidence of Anti-oxidative and Anti-inflammatory Effects. Abstract: BACKGROUND: Neuropathic pain responds poorly to drug treatments. The present study investigated the therapeutic effect of Portulaca oleracea, in chronic …
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