PMID: Int J Radiat Biol. 2017 11 ;93(11):1267-1273. PMID: 28903625 Abstract Title: Radioprotective activity of curcumin-encapsulated liposomes against genotoxicity caused by Gamma Cobalt-60 irradiation in human blood cells. Abstract: PURPOSE: While the radioprotective activity of curcumin against genotoxicity has been well established, its poor oral bioavailability has limited its successful clinical applications. Nanoscale formulations, including …
Category Archives: Uncategorized
Liposomes are a new strategy to target lipid rich inflammatory dendritic cells and have potential to deliver immunomodulatory compounds to treat NASH.
PMID: Metabolism. 2018 01 ;78:80-94. Epub 2017 Sep 20. PMID: 28941597 Abstract Title: Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Abstract: OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic macrophage inflammation, steatosis and fibrosis. Liposomes injected intravenously passively target hepatic myeloid cells and have potential to deliver immunomodulatory compounds and …
Graves Disease, an ‘Incurable’ Thyroid Disorder, Cured Through Lifestyle Changes
From incurable to a cure for an autoimmune disease – why not make lifestyle changes today that can improve your life and vitality?
Therapeutic potential of curcumin in major retinal pathologies.
PMID: Int Ophthalmol. 2019 Mar ;39(3):725-734. Epub 2018 Feb 5. PMID: 29404861 Abstract Title: Therapeutic potential of curcumin in major retinal pathologies. Abstract: PURPOSE: The retina is continually exposed to free radicals from its rich blood supply, numerous mitochondria, and photons of light which strike its surface. Most pathological processes that take place in the …
Continue reading “Therapeutic potential of curcumin in major retinal pathologies.”
Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy.
PMID: J Nanobiotechnology. 2018 Mar 23 ;16(1):28. Epub 2018 Mar 23. PMID: 29571289 Abstract Title: Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy. Abstract: BACKGROUND: The systemic administration of cytotoxic chemotherapeutic agents for cancer treatment often has toxic side effects, limiting the usage dose. To increase chemotherapeutic efficacy …
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
PMID: Int J Pharm. 2018 Jul 10 ;545(1-2):261-273. Epub 2018 May 3. PMID: 29730175 Abstract Title: Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma. Abstract: Hepatocellular carcinoma (HCC) continues to be a leading cause of cancer related death in the world. Conventional chemotherapeutic agents such as cisplatin (CDDP) have an unsatisfactory efficacy …
Enhancing curcumin oral bioavailability through nanoformulations.
PMID: Eur J Drug Metab Pharmacokinet. 2019 Aug ;44(4):459-480. PMID: 30771095 Abstract Title: Enhancing Curcumin Oral Bioavailability Through Nanoformulations. Abstract: Curcumin is a promising therapeutic agent that exhibits manifold therapeutic activities. However, it is challenging to study curcumin as it exhibits poor aqueous solubility and low permeability and it is a substrate for P-glycoprotein (P-gp). …
Continue reading “Enhancing curcumin oral bioavailability through nanoformulations.”
Do Synthetic Thyroid Hormones Work?
Doctors might fail to realize is that the symptoms of depression also double as symptoms of a commonly underdiagnosed condition–namely hypothyroidism
Liposomal curcumin is better than curcumin to alleviate complications in experimental diabetic mellitus.
PMID: Molecules. 2019 Feb 27 ;24(5). Epub 2019 Feb 27. PMID: 30818888 Abstract Title: Liposomal Curcumin is Better than Curcumin to Alleviate Complications in Experimental Diabetic Mellitus. Abstract: Curcumin (CC) is known to have anti-inflammatory and anti-oxidative properties and has already been tested for its efficiency in different diseases including diabetes mellitus (DM). New formulations …
Liposomal curcumin enhances the effect of naproxen in a model of migraine.
PMID: Med Sci Monit. 2019 Jul 9 ;25:5087-5097. Epub 2019 Jul 9. PMID: 31287810 Abstract Title: Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine. Abstract: BACKGROUND Curcumin is an antioxidant that reduces inflammation and pain. This study aimed to assess the effect of pretreatment with naproxen and liposomal curcumin compared …
Continue reading “Liposomal curcumin enhances the effect of naproxen in a model of migraine.”
Health Time 