PMID: Eur J Pharm Biopharm. 2019 Nov ;144:154-164. Epub 2019 Sep 19. PMID: 31542438 Abstract Title: Liposomes augment biological benefits of curcumin for multitargeted skin therapy. Abstract: Curcumin, a multi-targeting pharmacologically active compound, is a promising molecule for the treatment of skin inflammation and infection in chronic wounds. However, its hydrophobic nature remains to be …
Continue reading “Liposomes augment biological benefits of curcumin for multitargeted skin therapy.”
PMID: J Liposome Res. 2019 Nov 12:1-10. Epub 2019 Nov 12. PMID: 31631726 Abstract Title: Improved pharmacokinetics and reduced side effects of doxorubicin therapy by liposomal co-encapsulation with curcumin. Abstract: The goal of the current study was to investigate the pharmacokinetic profile, tissue distribution and adverse effects of long-circulating liposomes (LCL) with curcumin (CURC) and …
PMID: Anticancer Res. 2019 Mar ;39(3):1161-1168. PMID: 30842145 Abstract Title: Intense Uptake of Liposomal Curcumin by Multiple Myeloma Cell Lines: Comparison to Normal Lymphocytes, Red Blood Cells and Chronic Lymphocytic Leukemia Cells. Abstract: BACKGROUND/AIM: Curcumin is being widely investigated for its anticancer properties and several studies in the literature suggest that curcumin is distributed to …
Continue reading “Intense uptake of liposomal curcumin by multiple myeloma cell lines.”
PMID: Exp Ther Med. 2019 Nov ;18(5):3681-3687. Epub 2019 Sep 5. PMID: 31602247 Abstract Title: Tetrahydrocurcumin protects against spinal cord injury and inhibits the oxidative stress response by regulating FOXO4 in model rats. Abstract: It has been reported that tetrahydrocurcumin has hypoglycemic, hypolipidemic, anti-metastasis, anticancer and anti-depressant pharmacological effects, and its antioxidative, hypoglycemic and hypolipidemic …
PMID: Cancer Manag Res. 2019 ;11:6829-6840. Epub 2019 Jul 24. PMID: 31440081 Abstract Title: MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin. Abstract: The presence of glioma stem cells (GSCs) is thought to be a key factor responsible for development of the incurable glioblastoma multiforme (GBM). GSCs are often displayed during chemotherapy resistance, …
PMID: Med Sci Monit. 2019 Oct 4 ;25:7451-7458. Epub 2019 Oct 4. PMID: 31584928 Abstract Title: Curcumin Inhibits Cell Viability and Increases Apoptosis of SW620 Human Colon Adenocarcinoma Cells via the Caudal Type Homeobox-2 (CDX2)/Wnt/β-Catenin Pathway. Abstract: BACKGROUND Curcumin is a polyphenol compound extracted from the root of the herb Curcuma longa, which is used …
PMID: Curr Drug Metab. 2019 Oct 7. Epub 2019 Oct 7. PMID: 31589120 Abstract Title: Curcumin – A Novel Therapeutic Agent In The Prevention Of Colorectal Cancer. Abstract: BACKGROUND: Colorectal cancer is the third important cause of cancer-associated deaths across the world. Hence, there is an urgent need for understanding complete mechanism associated with colorectal …
Continue reading “Curcumin is a novel therapeutic agent in the prevention of colorectal cancer.”
PMID: Curr Mol Med. 2019 Oct 16. Epub 2019 Oct 16. PMID: 31622191 Abstract Title: Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury. Abstract: Curcumin is a naturally occurring polyphenol which is isolated from the rhizome of Curcuma longa (turmeric). This medicinal compound has different biological activities including antioxidant, antibacterial, antineoplastic, …
PMID: Nutrients. 2019 Oct 17 ;11(10). Epub 2019 Oct 17. PMID: 31627369 Abstract Title: Curcumin as a Therapeutic Strategy in Liver Diseases. Abstract: Liver diseases are classified as acute and chronic hepatic failures. In particular, chronic pathologies are the most common diseases in the World. Chronic pathologies of liver disease are the most common diseases …
Continue reading “Curcumin as a therapeutic strategy in liver diseases.”
PMID: J Proteomics. 2018 06 30 ;182:1-11. Epub 2018 Apr 22. PMID: 29684682 Abstract Title: Identification and validation nucleolin as a target of curcumol in nasopharyngeal carcinoma cells. Abstract: : Identification of the specific protein target(s) of a drug is a critical step in unraveling its mechanisms of action (MOA) in many natural products. Curcumol, …
Health Time