PMID: Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):100-106. PMID: 31041173 Abstract Title: Effect of Boswellia Serrata Extract on Acute Inflammatory Parameters and Tumor Necrosis Factor-α in Complete Freund's Adjuvant-Induced Animal Model of Rheumatoid Arthritis. Abstract: Context: The worldwide prevalence of rheumatoid arthritis (RA) is about 1%, whereas in India, it is approximately 0.75%. The …
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Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson’s disease.
PMID: Avicenna J Phytomed. 2019 May-Jun;9(3):281-290. PMID: 31143695 Abstract Title: Effects ofresin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson's disease. Abstract: Objective: oleo-gum resin (frankincense) exerted antioxidant and anti-inflammatory effects against several diseases, such as; asthma, rheumatoid arthritis and irritable bowel syndrome. In the current study, the influences …
The combination of bromelain and dexamethasone sodium phosphate induced a great activation of mesenchymal stem cells.
PMID: J Craniofac Surg. 2019 Jun ;30(4):1064-1067. PMID: 30358745 Abstract Title: In Vitro Effect of Bromelain on the Regenerative Properties of Mesenchymal Stem Cells. Abstract: BACKGROUND: Bromelain belongs to a group of protein-digesting enzymes obtained commercially from the fruit or stem of pineapple. Several studies demonstrated that bromelain exhibits various fibrinolytic, anti-edematous, antithrombotic, and anti-inflammatory …
Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis.
PMID: Anim Cells Syst (Seoul). 2018 ;22(5):334-340. Epub 2018 Aug 30. PMID: 30460115 Abstract Title: Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis. Abstract: Here, we investigated the possible anti-cancer properties of bromelain in Kras mutant human colorectal carcinoma cell lines and a mouse model harboring a Kras mutation. Cell growth and proliferation were …
Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy.
PMID: PLoS One. 2019 ;14(1):e0210274. Epub 2019 Jan 18. PMID: 30657763 Abstract Title: Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy. Abstract: Advanced colorectal cancer (CRC) survival rates are still low despite advances in cytotoxic and targeted therapies. The development of new effective or alternative therapies …
Evaluation of the radiosensitizing potency of bromelain for radiation therapy of 4T1 breast cancer cells.
PMID: J Med Signals Sens. 2019 Jan-Mar;9(1):68-74. PMID: 30967992 Abstract Title: Evaluation of the Radiosensitizing Potency of Bromelain for Radiation Therapy of 4T1 Breast Cancer Cells. Abstract: Breast cancer (BC) remains the leading cause of death in women worldwide, despite the improvements of cancer screening and treatment methods. Recently, development of novel anticancer drugs for …
The potential use of bromelain as a natural oral medicine having anticarcinogenic activities.
PMID: Food Sci Nutr. 2019 May ;7(5):1656-1667. Epub 2019 Apr 1. PMID: 31139378 Abstract Title: The potential use of bromelain as a natural oral medicine having anticarcinogenic activities. Abstract: Bromelain (BR), a protease extracted from, reportedly possesses pharmacological activities including the reduction of thrombogenesis, and antihypertensive, and antimicrobial effects. This study aimed to investigate the …
Bromelain plus peroxidase reduces non-Hodgkin lymphoma progression
PMID: Nutr Cancer. 2019 Oct 8:1-11. Epub 2019 Oct 8. PMID: 31591915 Abstract Title: Bromelain plus peroxidase reduces non-Hodgkin lymphoma progression invia up-regulation of antioxidant enzymes and modulating apoptotic protein expression. Abstract: Pineapple ((L.) Merr.) is a good source of bromelain (B) and also contain peroxidase. The objective of this study is isoaltion of bromelain …
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Bromelain mitigated electrolyte imbalance in chronic constricted injury of the sciatic nerve.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 26. Epub 2019 Oct 26. PMID: 31655851 Abstract Title: Bromelain reversed electrolyte imbalance in the chronically constricted sciatic nerve of Wistar rats. Abstract: Derangement of electrolyte in the sensory nervous system has been attributed to the development and maintenance of hyperalgesic and allodynic symptoms in painful neuropathy. This …
Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.
PMID: J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795 Abstract Title: Benefits of a Food Supplement Containingand Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. Abstract: Osteoarthritis (OA) is a joint disease involving articular cartilage degeneration causing patients pain, joint stiffness, physical disability, and …