Boswellia serrata extract might have usefulness as an adjunct to conventional therapy of rheumatoid arthritis.

PMID:  Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):100-106. PMID: 31041173 Abstract Title:  Effect of Boswellia Serrata Extract on Acute Inflammatory Parameters and Tumor Necrosis Factor-α in Complete Freund's Adjuvant-Induced Animal Model of Rheumatoid Arthritis. Abstract:  Context: The worldwide prevalence of rheumatoid arthritis (RA) is about 1%, whereas in India, it is approximately 0.75%. The …

Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson’s disease.

PMID:  Avicenna J Phytomed. 2019 May-Jun;9(3):281-290. PMID: 31143695 Abstract Title:  Effects ofresin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson's disease. Abstract:  Objective: oleo-gum resin (frankincense) exerted antioxidant and anti-inflammatory effects against several diseases, such as; asthma, rheumatoid arthritis and irritable bowel syndrome. In the current study, the influences …

The combination of bromelain and dexamethasone sodium phosphate induced a great activation of mesenchymal stem cells.

PMID:  J Craniofac Surg. 2019 Jun ;30(4):1064-1067. PMID: 30358745 Abstract Title:  In Vitro Effect of Bromelain on the Regenerative Properties of Mesenchymal Stem Cells. Abstract:  BACKGROUND: Bromelain belongs to a group of protein-digesting enzymes obtained commercially from the fruit or stem of pineapple. Several studies demonstrated that bromelain exhibits various fibrinolytic, anti-edematous, antithrombotic, and anti-inflammatory …

Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis.

PMID:  Anim Cells Syst (Seoul). 2018 ;22(5):334-340. Epub 2018 Aug 30. PMID: 30460115 Abstract Title:  Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis. Abstract:  Here, we investigated the possible anti-cancer properties of bromelain in Kras mutant human colorectal carcinoma cell lines and a mouse model harboring a Kras mutation. Cell growth and proliferation were …

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy.

PMID:  PLoS One. 2019 ;14(1):e0210274. Epub 2019 Jan 18. PMID: 30657763 Abstract Title:  Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy. Abstract:  Advanced colorectal cancer (CRC) survival rates are still low despite advances in cytotoxic and targeted therapies. The development of new effective or alternative therapies …

Evaluation of the radiosensitizing potency of bromelain for radiation therapy of 4T1 breast cancer cells.

PMID:  J Med Signals Sens. 2019 Jan-Mar;9(1):68-74. PMID: 30967992 Abstract Title:  Evaluation of the Radiosensitizing Potency of Bromelain for Radiation Therapy of 4T1 Breast Cancer Cells. Abstract:  Breast cancer (BC) remains the leading cause of death in women worldwide, despite the improvements of cancer screening and treatment methods. Recently, development of novel anticancer drugs for …

The potential use of bromelain as a natural oral medicine having anticarcinogenic activities.

PMID:  Food Sci Nutr. 2019 May ;7(5):1656-1667. Epub 2019 Apr 1. PMID: 31139378 Abstract Title:  The potential use of bromelain as a natural oral medicine having anticarcinogenic activities. Abstract:  Bromelain (BR), a protease extracted from, reportedly possesses pharmacological activities including the reduction of thrombogenesis, and antihypertensive, and antimicrobial effects. This study aimed to investigate the …

Bromelain plus peroxidase reduces non-Hodgkin lymphoma progression

PMID:  Nutr Cancer. 2019 Oct 8:1-11. Epub 2019 Oct 8. PMID: 31591915 Abstract Title:  Bromelain plus peroxidase reduces non-Hodgkin lymphoma progression invia up-regulation of antioxidant enzymes and modulating apoptotic protein expression. Abstract:  Pineapple ((L.) Merr.) is a good source of bromelain (B) and also contain peroxidase. The objective of this study is isoaltion of bromelain …

Bromelain mitigated electrolyte imbalance in chronic constricted injury of the sciatic nerve.

PMID:  Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 26. Epub 2019 Oct 26. PMID: 31655851 Abstract Title:  Bromelain reversed electrolyte imbalance in the chronically constricted sciatic nerve of Wistar rats. Abstract:  Derangement of electrolyte in the sensory nervous system has been attributed to the development and maintenance of hyperalgesic and allodynic symptoms in painful neuropathy. This …

Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.

PMID:  J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795 Abstract Title:  Benefits of a Food Supplement Containingand Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. Abstract:  Osteoarthritis (OA) is a joint disease involving articular cartilage degeneration causing patients pain, joint stiffness, physical disability, and …

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