PMID: J Diabetes Res. 2018 ;2018:5391014. Epub 2018 Sep 10. PMID: 30276216 Abstract Title: Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes. Abstract: Chronic inflammatory diseases like diabetes are on a rise in the Western world. Based on the tsunami of new cases every year, new therapeutic measures must be considered. A …
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Eugenol reduces LDL cholesterol and hepatic steatosis in hypercholesterolemia.
PMID: Sci Rep. 2019 Sep 30 ;9(1):14003. Epub 2019 Sep 30. PMID: 31570745 Abstract Title: Eugenol Reduces LDL Cholesterol and Hepatic Steatosis in Hypercholesterolemic Rats by Modulating TRPV1 Receptor. Abstract: Eugenol, a component of essential oils of medicinal and food plants, has a hypolipidemic effect in experimental animals although its mechanism of action is still …
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Eugenol exerts apoptotic effect and modulates the sensitivity of HeLa cells to cisplatin and radiation.
PMID: Molecules. 2019 Nov 3 ;24(21). Epub 2019 Nov 3. PMID: 31684176 Abstract Title: Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation. Abstract: Eugenol is a phytochemical present in different plant products, e.g., clove oil. Traditionally, it is used against a number of different disorders and it was …
Nobiletin has shown that it has protective effects by reducing kidney damage caused by ischemia-reperfusion injury.
PMID: Inflammation. 2019 Nov 8. Epub 2019 Nov 8. PMID: 31705353 Abstract Title: Nobiletin Protects from Renal Ischemia-Reperfusion Injury in Rats by Suppressing Inflammatory Cytokines and Regulating iNOS-eNOS Expressions. Abstract: Ischemia-reperfusion injury is an organ failure caused by hypoxia and reperfusion, which is closely associated with oxidative stress and inflammation. In this study, we investigated …
Daily consumption of pomegranate juice may stabilize the ability to learn visual information over a 12-month period.
PMID: Am J Clin Nutr. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31711104 Abstract Title: Randomized placebo-controlled study of the memory effects of pomegranate juice in middle-aged and older adults. Abstract: BACKGROUND: Antioxidant nutrients such as the polyphenols in pomegranate juice may prevent neuronal damage from the free radicals produced during normal metabolism. Previous …
Non-pharmacological management of gestational diabetes: The role of myo-inositol.
PMID: J Complement Integr Med. 2019 Sep 17. Epub 2019 Sep 17. PMID: 31527297 Abstract Title: Non-pharmacological management of gestational diabetes: The role of myo-inositol. Abstract: Gestational diabetes mellitus (GDM) is the most common metabolic disorder occurring in pregnancy. GDM plays an important role in the current diabetes epidemic: exposure to a high glycemic environment …
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Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF.
PMID: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):4089-4096. PMID: 31630562 Abstract Title: Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF. Abstract: The comprehensive pathological peculiarities of Neferine (NEF) have been testified in disparate diseases. But, the functions of NEF in choriocarcinoma progression remain unexplored. The research endeavoured to uncover …
Neferine mitigated renal injury in acute kidney injury models.
PMID: Front Pharmacol. 2019 ;10:1197. Epub 2019 Oct 15. PMID: 31680971 Abstract Title: Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression. Abstract: Morbidity associated with and mortality from acute kidney injury (AKI) is gradually increasing, and no efficient drug is available. We explored whether neferine, a bisbenzylisoquinoline alkaloid, attenuated AKI, …
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Blood-brain barrier-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells.
PMID: J Nat Med. 2019 Nov 9. Epub 2019 Nov 9. PMID: 31707550 Abstract Title: BBB-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells. Abstract: Blood-brain barrier (BBB)-permeable components in the methanolic extract of Nelumbo nucifera flowers showed accelerative effects on neurite outgrowth in PC-12 cells. Among the …
Neferine is a potential treatment for type 2 diabetes.
PMID: Front Pharmacol. 2019 ;10:999. Epub 2019 Sep 4. PMID: 31551792 Abstract Title: Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells. Abstract: Glucose transporter 4 (GLUT4) is involved in regulating glucose uptake in striated muscle, liver, and adipose tissue. Neferine is a dibenzyl isoquinoline alkaloid derived …
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