PMID: Neuroreport. 2019 Nov 6 ;30(16):1129-1134. PMID: 31568207 Abstract Title: Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo. Abstract: Epilepsy is one of the most widespread neurological diseases characterized by spontaneous recurrent seizures. There is no cure for epilepsy, and available pharmacological treatments with anti-seizure drugs are only …
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Myo-inositol was reported as an effective supplement for sperm quality.
PMID: Andrology. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31637826 Abstract Title: Myo-inositol in health and disease. Its impact upon semen parameters and male fertility. Abstract: BACKGROUND: Myo-inositol (cis-1,2,3,5-trans-4,6-cyclohexanehexol; MI) is the most prominent of nine Inositol stereoisomers. MI, its phosphate derivatives and associated lipids, are widely found in vegetables and animal tissues and …
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Inositol as putative integrative treatment for polycystic ovary syndrome.
PMID: Reprod Biomed Online. 2016 Dec ;33(6):770-780. Epub 2016 Sep 16. PMID: 27717596 Abstract Title: Inositol as putative integrative treatment for PCOS. Abstract: Studies over the last decade have demonstrated that some polycystic ovary syndrome (PCOS) patients have abnormal insulin sensitivity (insulin resistance), independently from being overweight or obese. This induces the risk of developing …
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Inositol supplementation in the prevention of gestational diabetes mellitus.
PMID: Cureus. 2019 Sep 16 ;11(9):e5671. Epub 2019 Sep 16. PMID: 31720147 Abstract Title: Inositol Supplementation in the Prevention of Gestational Diabetes Mellitus. Abstract: Inositol, an emerging novel therapy for the treatment of gestational diabetes mellitus (GDM), is a cyclic polyol that has insulin-like effects and plays an important role in glucose homeostasis. The conventional …
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Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis.
PMID: Cell Death Differ. 2019 Jun 17. Epub 2019 Jun 17. PMID: 31209359 Abstract Title: Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis. Abstract: Hypomagnesemia is a significant risk factor for critically ill patients to develop sepsis, a life-threatening disease with a mortality rate over 25%. Our clinic data analysis showed that hypomagnesemia …
Magnolol blocks migration in HCT116 cells by suppressing TGF-β signaling.
PMID: Front Oncol. 2019 ;9:752. Epub 2019 Oct 1. PMID: 31632899 Abstract Title: Magnolol Suppresses TGF-β-Induced Epithelial-to-Mesenchymal Transition in Human Colorectal Cancer Cells. Abstract: Tumor metastasis is the end state of a multistep process that includes dissemination of tumor cells to distant organs and requires tumor cells to adapt to different tissue microenvironments. During metastasis, …
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Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.
PMID: Environ Toxicol. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31714653 Abstract Title: Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma in vivo. Abstract: Although hepatitis B and/or hepatitis C virus were recognized as major risk factor for the development of hepatocellular carcinoma (HCC), certain occupational, environmental, and …
Magnolol protects PC12 cells from hydrogen peroxide or 6-hydroxydopamine induced cytotoxicity.
PMID: J Toxicol Sci. 2019 ;44(11):753-758. PMID: 31708532 Abstract Title: Magnolol protects PC12 cells from hydrogen peroxide or 6-hydroxydopamine induced cytotoxicity. Abstract: Magnoliae Cortex contains a range of bioactive components including terpenes (e.g.α-, β- and γ-eudesmol), phenylpropanoids (e.g. honokiol and magnolol) and alkaloids (e.g. magnocurarine). We recently reported that pretreatment of PC12 cells with Magnoliae …
Nutritional supplementation for the prevention and the treatment of gestational diabetes mellitus.
PMID: Curr Diab Rep. 2019 Aug 1 ;19(9):73. Epub 2019 Aug 1. PMID: 31368026 Abstract Title: Nutritional Supplementation for the Prevention and/or Treatment of Gestational Diabetes Mellitus. Abstract: PURPOSE OF REVIEW: Gestational diabetes mellitus (GDM) is a common pregnancy complication that has short- and long-term health implications for both the mother and child. While lifestyle …
One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.
PMID: Eur J Appl Physiol. 2019 Oct 17. Epub 2019 Oct 17. PMID: 31624951 Abstract Title: One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running. Abstract: PURPOSE: Magnesium supplementation modulates glucose metabolism and inflammation, which could influence exercise performance and recovery. This study investigated the …
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