Paeonol protects mitochondrial injury and prevents pulmonary vascular remodeling in hypoxia.

PMID:  Respir Physiol Neurobiol. 2019 Oct ;268:103252. Epub 2019 Jul 10. PMID: 31301382 Abstract Title:  Paeonol protects mitochondrial injury and prevents pulmonary vascular remodeling in hypoxia. Abstract:  Mitochondrial injury of pulmonary artery smooth muscle cells (PASMCs) is an important stage in the development of pulmonary arterial hypertension (PAH). Recent studies revealed that Paeonol exerts anti-proliferative …

Paeonol reverses adriamycin induced cardiac pathological remodeling.

PMID:  Chem Res Toxicol. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31307187 Abstract Title:  Paeonol Reverses Adriamycin Induced Cardiac Pathological Remodeling through Notch1 Signaling Reactivation in H9c2 Cells and Adult Zebrafish Heart. Abstract:  Adriamycin is a commonly prescribed chemotherapeutic drug for a wide range of cancers. Adriamycin causes cardiotoxicity as an adverse effect that …

Paeonol protects against hypertension in spontaneously hypertensive rats by restoring vascular endothelium.

PMID:  Biosci Biotechnol Biochem. 2019 Nov ;83(11):1992-1999. Epub 2019 Jul 31. PMID: 31362597 Abstract Title:  Paeonol protects against hypertension in spontaneously hypertensive rats by restoring vascular endothelium. Abstract:  The present study focused on the effect of paeonol, one of the main components of Guizhi Fuling Pill, on blood pressure, cerebral blood flow, and vascular endothelium …

Paeonol ameliorates monosodium urate-induced arthritis in rats through inhibiting nuclear factor-κB-mediated proinflammatory cytokine production.

PMID:  Phytother Res. 2019 Nov ;33(11):2971-2978. Epub 2019 Aug 12. PMID: 31407455 Abstract Title:  Paeonol ameliorates monosodium urate-induced arthritis in rats through inhibiting nuclear factor-κB-mediated proinflammatory cytokine production. Abstract:  Moutan Cortex has been widely used to treat various types of arthritis in traditional Chinese medicine. Paeonol is isolated as an active ingredient from Moutan Cortex. …

Anticonvulsant and neuroprotective effects of paeonol in epileptic rats.

PMID:  Neurochem Res. 2019 Nov ;44(11):2556-2565. Epub 2019 Sep 13. PMID: 31520267 Abstract Title:  Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats. Abstract:  Paeonol is the main active compound in the root bark extract of the peony tree, and it has antioxidative and anti-inflammatory effects. Recent studies have reported the neuroprotective effects of paeonol …

Gold nanoparticles synthesized using Paeonia mountan alleviates the neuroinflammation and improves the motor coordination in Parkinson induced mice.

n/a PMID:  J Photochem Photobiol B. 2019 Oct 16 ;200:111635. Epub 2019 Oct 16. PMID: 31671372 Abstract Title:  Neuroprotective effect of biosynthesised gold nanoparticles synthesised from root extract of Paeonia moutan against Parkinson disease – In vitro&In vivo model. Abstract:  Parkinson disease is one of the most common neurological movement disorders affecting geriatric population. Biosynthesized …

Edible tree peony flower is a potential functional food material and natural antioxidants resource.

PMID:  Foods. 2019 Oct 10 ;8(10). Epub 2019 Oct 10. PMID: 31658783 Abstract Title:  Phenolic Profile and Antioxidant Activity of the Edible Tree Peony Flower and Underlying Mechanisms of Preventive Effect on HO-Induced Oxidative Damage in Caco-2 Cells. Abstract:  The entire phenolic profiles and antioxidant activities of different organs of the edible tree peony flowers …

White peony polyphenols are high-quality natural products with liver protective effects.

PMID:  Antioxidants (Basel). 2019 Oct 31 ;8(11). Epub 2019 Oct 31. PMID: 31683564 Abstract Title:  White Peony (Fermented) Polyphenols Help Prevent Alcoholic Liver Injury via Antioxidation. Abstract:  White peony is a type of white tea () rich in polyphenols. In this study, polyphenols were extracted from white peony. In vitro experiments showed that white peony …

These results suggest that CBD may have potential as a new therapeutic target in gastric cancer.

PMID:  Cell Death Dis. 2019 Nov 7 ;10(11):846. Epub 2019 Nov 7. PMID: 31699976 Abstract Title:  Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer. Abstract:  According to recent studies, Cannabidiol (CBD), one of the main components of Cannabis sativa, has anticancer effects in several cancers. However, the exact mechanism of CBD action is …

Vitamin C is effective in preventing complex regional pain syndrome type I development after subacromial shoulder surgery.

PMID:  Eur J Orthop Surg Traumatol. 2019 Sep 20. Epub 2019 Sep 20. PMID: 31541301 Abstract Title:  Influence of vitamin C on the incidence of CRPS-I after subacromial shoulder surgery. Abstract:  PURPOSE: The primary aim of this study was to determine whether postoperative administration of vitamin C (VC) is associated with reduced risk of complex …

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