PMID: Int J Mol Sci. 2019 Dec 25 ;21(1). Epub 2019 Dec 25. PMID: 31881712 Abstract Title: Therapeutic Potential offor Depressive Disorder. Abstract: Depression is a common and severe neuropsychiatric disorder that is one of the leading causes of global disease burden. Although various anti-depressants are currently available, their efficacies are barely adequate and many …
Continue reading “Therapeutic potential of Hericium erinaceus for depressive disorders.”
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2019 Nov 25. Epub 2019 Nov 25. PMID: 31768573 Abstract Title: Effects of N-acetylcysteine amide on anxiety and stress behavior in zebrafish. Abstract: Anxiety disorders are highly prevalent and a leading cause of disability worldwide. Their etiology is related to stress, an adaptive response of the organism to restore homeostasis, …
Continue reading “Effects of N-acetylcysteine amide on anxiety and stress behavior in zebrafish.”
PMID: Antioxidants (Basel). 2019 Nov 24 ;8(12). Epub 2019 Nov 24. PMID: 31771272 Abstract Title: N-acetylcysteine Decreases Fibrosis and Increases Force-Generating Capacity ofDiaphragm. Abstract: Respiratory muscle weakness occurs due to dystrophin deficiency in Duchenne muscular dystrophy (DMD). Themouse model of DMD shows evidence of impaired respiratory muscle performance with attendant inflammation and oxidative stress. We …
PMID: J Child Adolesc Psychopharmacol. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31800306 Abstract Title: N-Acetylcysteine for Pediatric Obsessive-Compulsive Disorder: A Small Pilot Study. Abstract: Many children and adults with Obsessive-Compulsive Disorder (OCD) fail to respond to first-line pharmacological and behavioral treatments. Glutamate dysfunction may contribute to the development of OCD. N-acetylcysteine (NAC), a …
Continue reading “There may be some initial improvement in OCD symptom severity with NAC treatment.”
PMID: J Pain Res. 2019 ;12:3147-3159. Epub 2019 Nov 19. PMID: 31819599 Abstract Title: Ameliorative Effects Of N-Acetylcysteine As Adjunct Therapy On Symptoms Of Painful Diabetic Neuropathy. Abstract: Purpose: Painful diabetic neuropathy (PDN) is a variant of diabetic peripheral neuropathy which is highly prevalent and distressing in diabetic patients. Despite its high burden, the optimal …
Continue reading “N-acetylcysteine may alleviate painful symptoms of diabetic neuropathy.”
PMID: Sci Rep. 2019 Dec 10 ;9(1):18741. Epub 2019 Dec 10. PMID: 31822750 Abstract Title: Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression in a rat model. Abstract: The number of osteoarthritis patients is increasing with the rise in the number of elderly people in developed countries. Osteoarthritis, which causes joint pain and …
PMID: Aust N Z J Psychiatry. 2019 Dec 11:4867419893439. Epub 2019 Dec 11. PMID: 31826654 Abstract Title: Meta-analysis of randomised controlled trials with-acetylcysteine in the treatment of schizophrenia. Abstract: OBJECTIVE: There is accumulating evidence that adjunctive treatment with-acetylcysteine may be effective for schizophrenia. This study aimed to conduct a comprehensive meta-analysis examining the efficacy of …
PMID: Cureus. 2019 Nov 5 ;11(11):e6073. Epub 2019 Nov 5. PMID: 31832291 Abstract Title: N-acetylcysteine in the Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Abstract: Introduction Chronic obstructive pulmonary disease (COPD) is a preventable disease of the airways characterized by limited airflow. Acute exacerbations of COPD (AECOPD) may be precipitated by noxious stimuli. …
PMID: Biomolecules. 2019 Dec 17 ;9(12). Epub 2019 Dec 17. PMID: 31861240 Abstract Title: -Acetylcysteine Protects against the Anxiogenic Response to Cisplatin in Rats. Abstract: Since cisplatin therapy is usually accompanied with numerous toxicities, including neurotoxicity, that involve tissue oxidative damage, the aim of this study was to evaluate the possible protective effect of-acetylcysteine (NAC) …
Continue reading “N-acetylcysteine protects against the anxiogenic response to cisplatin.”
PMID: Antiviral Res. 2019 Dec 26:104699. Epub 2019 Dec 26. PMID: 31883926 Abstract Title: N-Acetyl cysteine effectively alleviates Coxsackievirus B-Induced myocarditis through suppressing viral replication and inflammatory response. Abstract: Viral myocarditis caused by Coxsackievirus B (CVB) infection is a severe inflammatory disease of the myocardium, which may develop to cardiomyopathy and heart failure. No effective …
Continue reading “N-Acetyl cysteine effectively alleviates coxsackievirus B-induced myocarditis.”
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