Aluminum can induce persistent itching nodules that itch for median time of 5 years.

PMID:  Eur J Pediatr. 2013 Feb ;172(2):171-7. Epub 2012 Oct 11. PMID: 23052615 Abstract Title:  Sixty-four children with persistent itching nodules and contact allergy to aluminium after vaccination with aluminium-adsorbed vaccines-prognosis and outcome after booster vaccination. Abstract:  UNLABELLED: Persistent itching subcutaneous nodules and aluminium (Al) allergy have been described after vaccination with Al-adsorbed vaccines but …

Molecular basis for Poria cocos mushroom polysaccharide used as an antitumor drug in China.

PMID:  Prog Mol Biol Transl Sci. 2019 ;163:263-296. Epub 2019 Apr 1. PMID: 31030751 Abstract Title:  Molecular basis for Poria cocos mushroom polysaccharide used as an antitumor drug in China. Abstract:  Poria cocos is an edible mushroom known as"Fuling"in Chinese, which belongs to the fungus family of Polyporaceae. Poria cocos has been used as a …

Isolation of homogeneous polysaccharide from Poria cocos and effect of its sulfated derivatives on migration of human breast cancer MDA-MB-231 cells.

PMID:  Zhongguo Zhong Yao Za Zhi. 2019 Jul ;44(13):2835-2840. PMID: 31359698 Abstract Title:  [Isolation of homogeneous polysaccharide from Poria cocos and effect of its sulfated derivatives on migration of human breast cancer MDA-MB-231 cells]. Abstract:  SATB1 plays a crucial role in the invasion and metastasis of breast cancer,and inhibition of SATB1 expression can effectively control …

16α-hydroxytrametenolic acid from Poria cocos improves intestinal barrier function.

PMID:  J Agric Food Chem. 2019 Oct 2 ;67(39):10871-10879. Epub 2019 Sep 23. PMID: 31517482 Abstract Title:  16α-Hydroxytrametenolic Acid fromImproves Intestinal Barrier Function Through the Glucocorticoid Receptor-Mediated PI3K/Akt/NF-κB Pathway. Abstract:  This study evaluated the effect of triterpenoids from edible mushroomon intestinal epithelium integrity and revealed the transcriptional regulatory pathways that underpin restorative mechanisms in the …

This suggested that Poria cocos Wolf can be potentially used for the treatment of hepatic steatosis.

PMID:  Int J Mol Sci. 2019 Sep 27 ;20(19). Epub 2019 Sep 27. PMID: 31569635 Abstract Title:  Wolf Extract Ameliorates Hepatic Steatosis through Regulation of Lipid Metabolism, Inhibition of ER Stress, and Activation of Autophagy via AMPK Activation. Abstract:  Wolf (PCW) is an edible, pharmaceutical mushroom with remarkable biological properties including anti-tumor, anti-inflammation, anti-oxidation, anti-ageing, …

Co-delivery of Poria cocos extract and doxorubicin as an ‘all-in-one’ nanocarrier to combat breast cancer multidrug resistance during chemotherapy.

PMID:  Nanomedicine. 2020 Jan ;23:102095. Epub 2019 Oct 25. PMID: 31669856 Abstract Title:  Co-delivery of Poria cocos extract and doxorubicin as an 'all-in-one' nanocarrier to combat breast cancer multidrug resistance during chemotherapy. Abstract:  Recent studies have indicated that multidrug resistance (MDR) can significantly limit the effects of conventional chemotherapy. In this study, PT (Pachymic acid …

Poria cocos polysaccharides may be a promising candidate for the therapy of atherosclerosis.

PMID:  Int Immunopharmacol. 2020 Jan 13 ;80:106173. Epub 2020 Jan 13. PMID: 31945610 Abstract Title:  Poria cocos polysaccharides attenuated ox-LDL-induced inflammation and oxidative stress via ERK activated Nrf2/HO-1 signaling pathway and inhibited foam cell formation in VSMCs. Abstract:  Oxidative stress, inflammation, and foam cell formation in vascular smooth muscle cells (VSMCs) are considered to play …

P. cocos may be considered as a traditional herbal potential medicine for the treatment of depression.

PMID:  J Ethnopharmacol. 2020 Jan 9. Epub 2020 Jan 9. PMID: 31926986 Abstract Title:  Poria cocos water extract ameliorates the behavioral deficits induced by unpredictable chronic mild stress in rats by down-regulating inflammation. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Poria cocos is a medicinal mushroom of the Polyporaceae family with antioxidant and anti-inflammatory activities, which has been used …

Purification of flavonoids from Chinese bayberry fruit extracts and α-glucosidase inhibitory activities.

PMID:  Molecules. 2016 Aug 31 ;21(9). Epub 2016 Aug 31. PMID: 27589714 Abstract Title:  Purification of Flavonoids from Chinese Bayberry (Morella rubra Sieb. et Zucc.) Fruit Extracts andα-Glucosidase Inhibitory Activities of Different Fractionations. Abstract:  Chinese bayberry (Morella rubra Sieb. et Zucc.) fruit have a diverse flavonoid composition responsible for the various medicinal activities, including anti-diabetes. …

Myricitrin protects against doxorubicin-induced cardiotoxicity.

PMID:  Evid Based Complement Alternat Med. 2016 ;2016:6093783. Epub 2016 Sep 14. PMID: 27703489 Abstract Title:  Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway. Abstract:  Doxorubicin (Dox) is one of the most effective and widely used anthracycline antineoplastic antibiotics. Unfortunately, the use of Dox is limited by …

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