Grape seed proanthocyanidins prevent H2O2-induced mitochondrial dysfunction and apoptosis

PMID:  J Food Biochem. 2020 Jan 14:e13147. Epub 2020 Jan 14. PMID: 31943241 Abstract Title:  Grape seed proanthocyanidins prevent HO-induced mitochondrial dysfunction and apoptosis via SIRT 1 activation in embryonic kidney cells. Abstract:  Grape proanthocyanidins are compounds widely ingested in the diet. This study evaluated their effects on mitochondrial function, apoptosis, and sirtuin 1 and …

Grape seed extract protected against cadmium-induced testicular toxicity.

PMID:  Folia Morphol (Warsz). 2020 Jan 13. Epub 2020 Jan 13. PMID: 31930466 Abstract Title:  The potential gonadoprotective effects of grape seed extract against the histopathological alterations elicited in an animal model of cadmium-induced testicular toxicity. Abstract:  BACKGROUND: Grape seed extract (GSE) is a powerful antioxidant containing high levels of bioflavonoids, vitamin C and vitamin …

Protective effects of ascorbic acid and calcitriol combination on airway remodelling in ovalbumin-induced chronic asthma.

PMID:  Pharm Biol. 2020 Dec ;58(1):107-115. PMID: 31942829 Abstract Title:  Protective effects of ascorbic acid and calcitriol combination on airway remodelling in ovalbumin-induced chronic asthma. Abstract:  Airway remodelling is one of the most refractory problems in asthma. According to the critical roles of oxidative stress and inflammation in airway remodelling, it is supposed that ascorbic …

Combination therapy with vitamin C could eradicate cancer stem cells.

PMID:  Biomolecules. 2020 Jan 3 ;10(1). Epub 2020 Jan 3. PMID: 31947879 Abstract Title:  Combination Therapy with Vitamin C Could Eradicate Cancer Stem Cells. Abstract:  Cancer remains one of the most feared and dreaded diseases in this era of modern medicine, claiming the lives of many, and affecting the quality of life of several others …

These results increase knowledge of the effect of gastrointestinal digestion on the biological effect of honey against colorectal cancer.

PMID:  Antioxidants (Basel). 2020 Jan 10 ;9(1). Epub 2020 Jan 10. PMID: 31936782 Abstract Title:  The Influence of In Vitro Gastrointestinal Digestion on the Anticancer Activity of Manuka Honey. Abstract:  Manuka honey (MH) is a natural food with many beneficial properties to human health, thanks to its high variety of bioactive compounds; however, little is …

Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor p,p’-DDE.

PMID:  Hum Reprod. 2014 Nov ;29(11):2512-21. Epub 2014 Sep 3. PMID: 25187598 Abstract Title:  Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor p,p'-DDE. Abstract:  STUDY QUESTION: What are the epigenetic mechanisms underlying the transgenerational effect of p,p'-DDE on male fertility?SUMMARY ANSWER: Impaired male fertility with …

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.

PMID:  PLoS One. 2017 ;12(5):e0176155. Epub 2017 May 2. PMID: 28464002 Abstract Title:  Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish. Abstract:  Methylmercury (MeHg) is a ubiquitous environmental neurotoxicant, with human exposures predominantly resulting from fish consumption. Developmental exposure of zebrafish to MeHg is known to alter their neurobehavior. …

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

PMID:  BMC Med. 2013 Oct 23 ;11:228. Epub 2013 Oct 23. PMID: 24228800 Abstract Title:  Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity. Abstract:  BACKGROUND: Ancestral environmental exposures to a variety of environmental factors and toxicants have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The present work examined …

Design a site like this with WordPress.com
Get started