PMID: Molecules. 2017 Jun 20 ;22(6). Epub 2017 Jun 20. PMID: 28632185 Abstract Title: The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines. Abstract: β-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER) and valencene (VAL) are constituents of the essential oil of(MEO), which …
Author Archives: Taylor Mercado
The evidence suggested myricanol may potentially serve as a remedy for prevention and therapy of neurodegenerative diseases induced by oxidative stress.
PMID: Molecules. 2017 Jul 24 ;22(7). Epub 2017 Jul 24. PMID: 28737731 Abstract Title: Study on Chemical Profile and Neuroprotective Activity of Myrica rubra Leaf Extract. Abstract: The chemical profile of(a native species in China) leaf extract was investigated by UPLC-PDA-HRMS, and the neuroprotective activity of two characteristic constituents, myricanol and myricetrin, was evaluated with …
Dietary compound proanthocyanidins from Chinese bayberry leaves attenuate chemotherapy-resistant ovarian cancer stem cell traits.
PMID: Food Funct. 2018 Jan 24 ;9(1):525-533. PMID: 29256569 Abstract Title: Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves attenuate chemotherapy-resistant ovarian cancer stem cell traits via targeting the Wnt/β-catenin signaling pathway and inducing G1 cell cycle arrest. Abstract: Cancer stem cells (CSCs) represent a small population of cancer cells characterized …
Bayberry leaves proanthocyanidin could be a valuable resource of natural compounds for cancer treatment.
PMID: J Funct Foods. 2018 Jan ;40:573-581. Epub 2017 Dec 22. PMID: 29576805 Abstract Title: Dietary Compound Proanthocyanidins from Chinese bayberry (Sieb. et Zucc.) leaves inhibit angiogenesis and regulate cell cycle of cisplatin-resistant ovarian cancer cells via targeting Akt pathway. Abstract: Ovarian cancer is the leading cause of death from gynecological malignancy and natural products …
Protection of anthocyanin from Myrica rubra against cerebral ischemia-reperfusion injury.
PMID: Molecules. 2018 Jul 20 ;23(7). Epub 2018 Jul 20. PMID: 30036952 Abstract Title: Protection of Anthocyanin fromagainst Cerebral Ischemia-Reperfusion Injury via Modulation of the TLR4/NF-κB and NLRP3 Pathways. Abstract: (MR) is rich in anthocyanins, and it has good anti-cancer, anti-aging, antioxidant, and antiviral effects. The proportion of disability and death caused by ischemic stroke …
The results indicate that myricanol could be a potential therapeutic agent against obesity by activating the AMPK signaling pathway.
PMID: Food Chem. 2019 Jan 1 ;270:305-314. Epub 2018 Jul 18. PMID: 30174051 Abstract Title: Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase. Abstract: Myricanol is a diarylheptanoid isolated from Chinese bayberry. Through virtual docking strategy, myricanol was discovered as an AMP-activated protein kinase (AMPK) activator …
Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury.
PMID: Int J Mol Med. 2019 May ;43(5):2133-2143. Epub 2019 Mar 12. PMID: 30864694 Abstract Title: Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway. Abstract: Myrica rubra is well known for its delicious taste and high nutritional value. The present study investigated the potential protective effects and …
Health-promoting properties of proanthocyanidins for intestinal dysfunction.
PMID: Nutrients. 2020 Jan 2 ;12(1). Epub 2020 Jan 2. PMID: 31906505 Abstract Title: Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction. Abstract: The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and …
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Allicin can suppress human epidural scar fibroblasts migration, induce cell apoptosis, and block cell proliferation at S phase and G2 phase.
PMID: World Neurosurg. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31953094 Abstract Title: Allicin inhibits proliferation and promotes apoptosis of human epidural scar fibroblasts. Abstract: BACKGROUND: Allicin can suppress liver and cardiac fibrosis, thus we hypothesize that it may prevent scar tissue from extensive epidural fibrosis after laminectomy.METHODS: Human epidural scar fibroblasts were isolated …
Association of total flavonoid intake with hypo-HDL-cholesterolemia among Korean adults: effect modification by polyunsaturated fatty acid intake.
PMID: Nutrients. 2020 Jan 10 ;12(1). Epub 2020 Jan 10. PMID: 31936778 Abstract Title: Association of Total Flavonoid Intake with Hypo-HDL-Cholesterolemia among Korean Adults: Effect Modification by Polyunsaturated Fatty Acid Intake. Abstract: The aim of this study was to examine the independent association between flavonoid intake and hypo-high-density lipoprotein (HDL)-cholesterolemia and the potential modifying effect …
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