PMID: Environ Sci Pollut Res Int. 2020 Jan 8. Epub 2020 Jan 8. PMID: 31916151 Abstract Title: Protective role of lycopene against metabolic disorders induced by chronic bisphenol A exposure in rats. Abstract: This study was conducted to elucidate the ameliorative potential of lycopene (LYC) against the metabolic toxicity induced by bisphenol A (BPA) in …
Author Archives: Taylor Mercado
Benzyl isothiocyanate triggers apoptosis in gastric adenocarcinoma cells.
PMID: Biomolecules. 2019 Dec 6 ;9(12). Epub 2019 Dec 6. PMID: 31817791 Abstract Title: Benzyl Isothiocyanate Induces Apoptosis via Reactive Oxygen Species-Initiated Mitochondrial Dysfunction and DR4 and DR5 Death Receptor Activation in Gastric Adenocarcinoma Cells. Abstract: Benzyl isothiocyanate (BITC) is known to inhibit the metastasis of gastric cancer cells but further studies are needed to …
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Neuroprotective effects of quercetin in Alzheimer’s disease.
PMID: Biomolecules. 2019 Dec 30 ;10(1). Epub 2019 Dec 30. PMID: 31905923 Abstract Title: Neuroprotective Effects of Quercetin in Alzheimer's Disease. Abstract: Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic potential. It is widely distributed among plants and found commonly in daily diets predominantly in fruits and vegetables. Neuroprotection by quercetin has …
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Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis.
PMID: Int J Biol Sci. 2020 ;16(1):147-161. Epub 2020 Jan 1. PMID: 31892852 Abstract Title: Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis. Abstract: Colorectal carcinoma (CRC) is the third most common malignant tumor pathology worldwide. Despite progress in surgical procedures and therapy options, CRC is still a considerable cause …
Myricetin abrogates cisplatin-induced oxidative stress, inflammatory response, and goblet cell disintegration in the colon.
PMID: Plants (Basel). 2019 Dec 24 ;9(1). Epub 2019 Dec 24. PMID: 31878169 Abstract Title: Myricetin Abrogates Cisplatin-Induced Oxidative Stress, Inflammatory Response, and Goblet Cell Disintegration in Colon of Wistar Rats. Abstract: Cisplatin [cis-diamminedichloroplatinum II] is an extensively prescribed drug in cancer chemotherapy; it is also useful for the treatment of diverse types of malignancies. …
Myricetin alleviates pathological cardiac hypertrophy.
PMID: Oxid Med Cell Longev. 2019 ;2019:6304058. Epub 2019 Dec 6. PMID: 31885808 Abstract Title: Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway. Abstract: Myricetin (Myr) is a common plant-derived polyphenol and is well recognized for its multiple activities including antioxidant, anti-inflammation, anticancer, and antidiabetes. Our previous studies indicated that Myr protected …
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The protective effects of myricetin against cardiovascular disease.
PMID: J Nutr Sci Vitaminol (Tokyo). 2019 ;65(6):470-476. PMID: 31902859 Abstract Title: The Protective Effects of Myricetin against Cardiovascular Disease. Abstract: Cardiovascular disease (CVD) is the leading cause of death globally, except Africa, and poses a severe health burden worldwide. Both in vitro and in vivo studies have demonstrated the protective effects of myricetin for …
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Sulforaphane exhibits cytotoxic effects against primary effusion lymphoma cells.
PMID: Biol Pharm Bull. 2019 ;42(12):2109-2112. PMID: 31787726 Abstract Title: Sulforaphane Exhibits Cytotoxic Effects against Primary Effusion Lymphoma Cells by Suppressing p38MAPK and AKT Phosphorylation. Abstract: Primary effusion lymphoma (PEL) is a rare subtype of non-Hodgkin's B-cell lymphoma and is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) in immunosuppressed patients. PEL is an aggressive lymphoma and …
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Methanol soluble fraction of fruits of Annona muricata possesses significant antidiarrheal activities.
PMID: Heliyon. 2020 Jan ;6(1):e03112. Epub 2019 Dec 31. PMID: 31909276 Abstract Title: Methanol soluble fraction of fruits ofpossesses significant antidiarrheal activities. Abstract: Medicinal plants are the major sources of traditional treatment of disease in Indian subcontinent due to abundant presence of plants and vast side effects of synthetic drug. The present study was subjected …
Ginkgo biloba leaf extract may be therapeutically effective in improving behavioral score in cerebral ischemia-reperfusion injury.
PMID: J Toxicol Environ Health A. 2019 ;82(19):1045-1051. Epub 2019 Nov 18. PMID: 31735125 Abstract Title: Mechanisms Associated with Protective Effects of Ginkgo Biloba Leaf Extracton in Rat Cerebral Ischemia Reperfusion Injury. Abstract: Cerebral infarction occurs as a consequence of cerebral ischemia-reperfusion injury (CIRI).leaf extract (GbE) is composed predominantly of active ingredients such as flavonoids …
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