PMID: Food Chem Toxicol. 2018 Oct ;120:407-417. Epub 2018 Jul 25. PMID: 30055311 Abstract Title: Licochalcone A from licorice root, an inhibitor of human hepatoma cell growth via induction of cell apoptosis and cell cycle arrest. Abstract: We investigated the anti-cancer activity of Licochalcone A (LCA), extracted from licorice root. LCA inhibited the proliferation of …
Continue reading “Licochalcone A from licorice root, an inhibitor of human hepatoma cell growth.”
PMID: Food Funct. 2018 Aug 15 ;9(8):4500-4507. PMID: 30083664 Abstract Title: Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest. Abstract: Licochalcone A (LA), an active ingredient of licorice, has multiple biological activities, including antioxidative and anti-inflammatory activities. Although LA exerts antitumor effects in various cancer cells, its role …
PMID: Phytother Res. 2018 Dec ;32(12):2551-2559. Epub 2018 Oct 3. PMID: 30281174 Abstract Title: Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome. Abstract: Activation of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome by Propionibacterium acnes (P. acnes) is critical for inducing inflammation and aggravating the development of acne lesions. We …
PMID: Zhongguo Zhong Yao Za Zhi. 2018 Sep ;43(17):3545-3552. PMID: 30347925 Abstract Title: [Effect of licochalcone A on autophagy in renal cell carcinoma via PI3K/Akt/mTOR signaling pathway]. Abstract: To investigate the effect of licochalcone (LCA) on autophagy in renal cell carcinoma (RCC), and further determine whether the mechanism is correlated with the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian …
PMID: Food Funct. 2018 Dec 13 ;9(12):6196-6204. PMID: 30465574 Abstract Title: Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways. Abstract: Licochalcone A (LicA) has been reported to possess antitumor properties. However, its effect on human glioma cells remains unknown. In this study, we observed that …
PMID: Cells. 2019 03 5 ;8(3). Epub 2019 Mar 5. PMID: 30841634 Abstract Title: Licochalcone A Inhibits Cellular Motility by Suppressing E-cadherin and MAPK Signaling in Breast Cancer. Abstract: A compound isolated from, licochalcone A (LA) exhibits anti-inflammatory and anti-tumor properties in various cell lines. LA has been found to promote autophagy and suppress specificity …
PMID: Environ Toxicol. 2019 Jul ;34(7):853-860. Epub 2019 Apr 14. PMID: 30983163 Abstract Title: Licochalcone A induces apoptotic cell death via JNK/p38 activation in human nasopharyngeal carcinoma cells. Abstract: Licochalcone A is widely studied in different fields and possesses antiasthmatic, antibacterial, anti-inflammatory, antioxidative, and anticancer properties. Its antimalignancy activity on renal, liver, lung, and oral …
PMID: Pharmacol Res. 2019 06 ;144:210-226. Epub 2019 Apr 22. PMID: 31022523 Abstract Title: Natural products in licorice for the therapy of liver diseases: Progress and future opportunities. Abstract: Liver diseases related complications represent a significant source of morbidity and mortality worldwide, creating a substantial economic burden. Oxidative stress, excessive inflammation, and dysregulated energy metabolism …
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PMID: Cells. 2019 05 11 ;8(5). Epub 2019 May 11. PMID: 31083505 Abstract Title: Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet. Abstract: Licochalcone A is a chalcone isolated from. It showed anti-tumor and anti-inflammatory properties in mice with …
PMID: Cells. 2019 06 20 ;8(6). Epub 2019 Jun 20. PMID: 31226782 Abstract Title: Protective Effects of Licochalcone A Improve Airway Hyper-Responsiveness and Oxidative Stress in a Mouse Model of Asthma. Abstract: Licochalcone A was isolated fromand previously reported to have antitumor and anti-inflammatory effects. Licochalcone A has also been found to inhibit the levels …
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