PMID: Neuropsychiatr Dis Treat. 2019 ;15:3041-3050. Epub 2019 Oct 29. PMID: 31754303 Abstract Title: Extract Reduces Hippocampus Inflammatory Responses, Improves Cardiac Functions And Depressive Behaviors In A Heart Failure Mouse Model. Abstract: Background: Depression has been shown to share an extremely high comorbidity with heart failure (HF).extract (GBE) is a widely used traditional Chinese medicine …
Author Archives: Taylor Mercado
Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway.
PMID: PLoS One. 2019 ;14(12):e0225761. Epub 2019 Dec 2. PMID: 31790465 Abstract Title: Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway. Abstract: BACKGROUND: Standardized Ginkgo biloba extract (GBE) has demonstrated efficacy in the cognitive functional neuropsychiatric symptoms of patients with Alzheimer's disease (AD). With regard to its underlying molecular mode of action, …
Ginkgo biloba leaf extract protects HepG2 cells against paraquat-induced oxidative DNA damage.
PMID: Plants (Basel). 2019 Nov 29 ;8(12). Epub 2019 Nov 29. PMID: 31795413 Abstract Title: L. Leaf Extract Protects HepG2 Cells Against Paraquat-Induced Oxidative DNA Damage. Abstract: L. leaf extracts and herbal infusions are used worldwide due to the health benefits that are attributed to its use, including anti-neoplastic, anti-aging, neuro-protection, antioxidant and others. The …
In vivo protective effects of Ginkgo biloba L. leaf extract against hydrogen peroxide toxicity: cytogenetic and biochemical evaluation.
PMID: Environ Sci Pollut Res Int. 2019 Dec 14. Epub 2019 Dec 14. PMID: 31838678 Abstract Title: In vivo protective effects of Ginkgo biloba L. leaf extract against hydrogen peroxide toxicity: cytogenetic and biochemical evaluation. Abstract: In this study, the protective effects of Ginkgo biloba leaf extract (GbE) against toxicity induced by hydrogen peroxide (HO) …
Ginkgo biloba prevents the symptoms of aluminium induced Alzheimer’s disease like pathophysiolog.
PMID: Neurochem Res. 2020 Jan 2. Epub 2020 Jan 2. PMID: 31894463 Abstract Title: Modulatory Effects of Ginkgo biloba Against Amyloid Aggregation Through Induction of Heat Shock Proteins in Aluminium Induced Neurotoxicity. Abstract: Protein misfolding and aggregation of amyloid beta (Aβ) peptide, as well as formation of neurofibrillary tangles (NFTs) are the signature hallmarks of …
Kaempferol protects against cadmium chloride-induced memory loss and hippocampal apoptosis.
PMID: Neurochem Res. 2019 Nov 25. Epub 2019 Nov 25. PMID: 31768814 Abstract Title: Kaempferol Protects Against Cadmium Chloride-Induced Memory Loss and Hippocampal Apoptosis by Increased Intracellular Glutathione Stores and Activation of PTEN/AMPK Induced Inhibition of Akt/mTOR Signaling. Abstract: This study investigated the protective effect of Kaempferol against CdCl-induced hippocampal damage and memory deficit in …
Kaempferol is a promising therapeutic candidate for treatment of prostate cancer.
PMID: Anal Cell Pathol (Amst). 2019 ;2019:1907698. Epub 2019 Dec 1. PMID: 31871879 Abstract Title: Kaempferol Promotes Apoptosis While Inhibiting Cell Proliferation via Androgen-Dependent Pathway and Suppressing Vasculogenic Mimicry and Invasion in Prostate Cancer. Abstract: Kaempferol is a well-known natural flavonol reported to be a potential treatment for multiple cancers. In this study, we demonstrated …
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Ginkgo biloba extract appears to improve neurological function and dependence compared with conventional therapy for ischemic stroke.
PMID: Medicine (Baltimore). 2020 Jan ;99(2):e18568. PMID: 31914035 Abstract Title: Ginkgol Biloba extract as an adjunctive treatment for ischemic stroke: A systematic review and meta-analysis of randomized clinical trials. Abstract: OBJECTIVE: Ginkgo biloba extract (GBE) is widely used as an adjunctive treatment for ischemic stroke. This meta-analysis aimed to evaluate the effectiveness and safety of …
Licochalcone A upregulates Nrf2 antioxidant pathway and thereby alleviates acetaminophen-induced hepatotoxicity.
PMID: Front Pharmacol. 2018 ;9:147. Epub 2018 Mar 23. PMID: 29628888 Abstract Title: Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity. Abstract: Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2-related factor 2 (Nrf2) is involved in prevention of hepatotoxicity. Although Licochalcone A …
Licochalcone A: An effective and low-toxicity compound against Toxoplasma gondii.
PMID: Int J Parasitol Drugs Drug Resist. 2018 08 ;8(2):238-245. Epub 2018 Mar 1. PMID: 29684680 Abstract Title: Licochalcone A: An effective and low-toxicity compound against Toxoplasma gondii in vitro and in vivo. Abstract: Toxoplasma gondii, an obligate intracellular protozoan, is the causative agent of toxoplasmosis, which can cause serious public health problems. The current …
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