PMID: Food Funct. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31830168 Abstract Title: Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma. Abstract: Ginsenoside Rk1 is a substance derived from ginseng and exhibits various activities such as anti-diabetic, anti-inflammatory and anti-cancer effects; however, its anti-tumor …
Author Archives: Taylor Mercado
These findings highlighted the potential use of ginsenoside Rg3R in clinical applications for colorectal cancer treatment.
PMID: Onco Targets Ther. 2019 ;12:10885-10895. Epub 2019 Dec 11. PMID: 31849492 Abstract Title: 20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis. Abstract: Background: Cancer stem cells (CSCs) have been proposed as central drivers of cancer relapse in many cancers. In the present study, …
Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-kB/NLRP3 pathway.
PMID: J Cell Biochem. 2019 Nov 11. Epub 2019 Nov 11. PMID: 31709615 Abstract Title: Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-kB/NLRP3 pathway. Abstract: Sepsis-induced myocardial dysfunction (SIMD) causes high mortality in seriously ill patients. Ginsenoside Rg1 has been proven to have effective anti-inflammatory and antiapoptotic properties. However, the specific role of …
The protective mechanisms underlying Ginsenoside Rg1 effects on rat sciatic nerve injury.
PMID: J Toxicol Environ Health A. 2019 ;82(19):1027-1035. Epub 2019 Nov 18. PMID: 31739751 Abstract Title: The protective mechanisms underlying Ginsenoside Rg1 effects on rat sciatic nerve injury. Abstract: Ginsenoside Rg1 (GsRg1), derived from the herb Ginseng, was found to exert protective effects in nerve injury; however, the mechanisms underlying these effects remain to be …
Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetes.
PMID: Eur J Pharmacol. 2020 Jan 5 ;866:172801. Epub 2019 Nov 16. PMID: 31738935 Abstract Title: Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetic by modulating the NLRP3 and Keap1/Nrf2/HO-1 pathways. Abstract: Ginseng has been traditionally used to treat diabetes mellitus (DM) in China. Ginsenoside Rg1 is a major active ingredient in processed ginseng, …
Continue reading “Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetes.”
These findings provide a new biological target of ginsenoside Rg1 for the treatment of neuroinflammatory disorders.
PMID: Front Neurosci. 2019 ;13:1168. Epub 2019 Nov 7. PMID: 31787867 Abstract Title: Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation. Abstract: Neuroinflammation plays a pivotal role in the pathogenesis of Parkinson's disease. Ginsenoside Rg1, the most active ingredient of ginseng, has been reported to exert neuroprotective effects via …
Ginsenoside Rb1 increases macrophage phagocytosis through p38 mitogen-activated protein kinase/Akt pathway.
PMID: J Ginseng Res. 2019 Jul ;43(3):394-401. Epub 2018 Jun 2. PMID: 31308811 Abstract Title: Ginsenoside Rb1 increases macrophage phagocytosis through p38 mitogen-activated protein kinase/Akt pathway. Abstract: Background: Ginsenoside Rb1, a triterpene saponin, is derived from theroot and has potent antiinflammatory activity. In this study, we determined if Rb1 can increase macrophage phagocytosis and elucidated the …
Prepregnancy acetaminophen use may be associated with higher risk of adverse birth outcomes.
PMID: Pediatr Res. 2019 Dec 18. Epub 2019 Dec 18. PMID: 31852009 Abstract Title: Association between maternal acetaminophen use and adverse birth outcomes in a pregnancy and birth cohort. Abstract: INTRODUCTION: Acetaminophen is the only analgesic recommended for use during pregnancy. This use has recently been linked to childhood developmental disorders, a finding that requires …
Fermented black ginseng has beneficial effects on wound healing.
PMID: J Ginseng Res. 2018 Oct ;42(4):524-531. Epub 2017 Jul 25. PMID: 30337813 Abstract Title: Effects of fermented black ginseng on wound healing mediated by angiogenesis through the mitogen-activated protein kinase pathway in human umbilical vein endothelial cells. Abstract: Background: Fermented black ginseng (FBG) is produced through several cycles of steam treatment of raw ginseng, …
Continue reading “Fermented black ginseng has beneficial effects on wound healing.”
Black ginseng may be useful as an alternative antiviral adjuvant to modulate immune responses to influenza A virus.
PMID: Nutrients. 2019 Aug 13 ;11(8). Epub 2019 Aug 13. PMID: 31412594 Abstract Title: Greater Efficacy of Black Ginseng (CJ EnerG) over Red Ginseng against Lethal Influenza A Virus Infection. Abstract: Black ginseng (BG, CJ EnerG), prepared via nine repeated cycles of steaming and drying of fresh ginseng, contains more accessible acid polysaccharides and smaller …
Health Time 