Author Archives: Taylor Mercado

PMID:  Int J Ophthalmol. 2019 ;12(10):1531-1538. Epub 2019 Oct 18. PMID: 31637187 Abstract Title:  Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells. Abstract:  AIM: To explore the effect of parthenolide (PTL) on human uveal melanoma (UM) cells (C918 and SP6.5 cells) and its molecular mechanism.METHODS: Carboxyfluorescein succinimidyl amino ester (CFSE) …

Continue reading “Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells.”

PMID:  Sci Rep. 2019 Dec 18 ;9(1):19370. Epub 2019 Dec 18. PMID: 31852965 Abstract Title:  Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p. Abstract:  Sepsis is a life-threatening disease caused by infection. Inflammation is a key pathogenic process in sepsis. Paeonol, an active ingredient in moutan cortex (a Chinese herb), has many pharmacological activities, …

Continue reading “Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p.”

Are aching, swollen joints stifling your activity levels and making life a real pain? Read on to learn how ginger, an inexpensive, herbal wonder, can lead to less pain and inflammation

PMID:  Pharmacol Ther. 2019 Dec 10:107452. Epub 2019 Dec 10. PMID: 31836457 Abstract Title:  Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony. Abstract:  As a Traditional Chinese Medicine, Paeonia lactiflora Pallas has been used to treat pain, inflammation and immune disorders for more than 1000 years in China. Total glycoside of paeony (TGP) …

Continue reading “Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony.”

PMID:  Pharmacol Ther. 2019 Dec 10:107452. Epub 2019 Dec 10. PMID: 31836457 Abstract Title:  Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony. Abstract:  As a Traditional Chinese Medicine, Paeonia lactiflora Pallas has been used to treat pain, inflammation and immune disorders for more than 1000 years in China. Total glycoside of paeony (TGP) …

Continue reading “Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony.”

PMID:  Curr Pharm Biotechnol. 2019 Dec 24. Epub 2019 Dec 24. PMID: 31884927 Abstract Title:  Protective effect of paeoniflorin on acute cerebral infarction in rats. Abstract:  The purpose of this paper was to study the protective effect of paeoniflorin on acute cerebral ischemia. The animal model of cerebral infarction induced by middle cerebral artery occlusion …

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PMID:  Int Immunopharmacol. 2019 Dec 12 ;78:106064. Epub 2019 Dec 12. PMID: 31838448 Abstract Title:  Parthenolide, an NF-κB inhibitor, alleviates peritoneal fibrosis by suppressing the TGF-β/Smad pathway. Abstract:  Transforming growth factor (TGF)-β/Smad signalling plays a central role in the pathogenesis of peritoneal fibrosis related to peritoneal dialysis (PD). Parthenolide (PTL), a naturally occurring phytochemical, is …

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PMID:  Cancers (Basel). 2019 Dec 22 ;12(1). Epub 2019 Dec 22. PMID: 31877856 Abstract Title:  Honokiol: A Review of Its Anticancer Potential and Mechanisms. Abstract:  Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is largely caused by a variety of gene mutations. There are continuous efforts being made to develop effective …

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PMID:  J Microbiol Biotechnol. 2019 Nov 6. Epub 2019 Nov 6. PMID: 31693840 Abstract Title:  Inhibition of Herpes Simplex Viruses, Types 1 and 2, by Ginsenoside 20(S)-Rg3. Abstract:  Infections by herpes simplex viruses have an immense impact on humans, ranging from self-limiting, benign illness to serious, life-threatening diseases. While nucleoside analog drugs are available, resistance …

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n/a PMID:  J Ginseng Res. 2019 Oct ;43(4):550-561. Epub 2018 Apr 9. PMID: 31695563 Abstract Title:  Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice. Abstract:  Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains …

Continue reading “20 (S)-ginsenoside Rg3 can inhibit the formation of gastric ulcer.”