PMID: Clin Exp Allergy. 2013 Feb ;43(2):249-54. PMID: 23331566 Abstract Title: Hypersensitivity reactions to the Sabin vaccine in children with cow's milk allergy. Abstract: BACKGROUND: The Sabin vaccine is used world-wide, and most children with food allergies receive it without incident. However, in the 2009 vaccination campaign conducted in Argentina, four children experienced immediate-type hypersensitivity …
Author Archives: Taylor Mercado
Both the inactivated polio virus vaccine and the oral polio virus vaccine create the risk of vaccine-related polio. What do they really solve?
PMID: N Engl J Med. 2014 Oct 16 ;371(16):1476-9. PMID: 25317869 Abstract Title: Achieving and maintaining polio eradication–new strategies. Abstract: [n/a] read more
Evidence of significant conflicts of interest in vaccine research.
PMID: Vaccine. 2015 May 21 ;33(22):2594-601. Epub 2015 Apr 14. PMID: 25882172 Abstract Title: Immunogenicity and reactogenicity of a decennial booster dose of a combined reduced-antigen-content diphtheria-tetanus-acellular pertussis and inactivated poliovirus booster vaccine (dTpa-IPV) in healthy adults. Abstract: BACKGROUND: Pertussis in adults and adolescents could be reduced by replacing traditional tetanus and diphtheria (Td) boosters …
Continue reading “Evidence of significant conflicts of interest in vaccine research.”
Concern remains whether immunity induced by a single IPV dose will prevent the emergence of circulating vaccine-derived type-2 poliovirus after removal of Sabin type-2 virus.
PMID: Clin Infect Dis. 2018 10 30 ;67(suppl_1):S35-S41. PMID: 30376081 Abstract Title: Immunogenicity of New Primary Immunization Schedules With Inactivated Poliovirus Vaccine and Bivalent Oral Polio Vaccine for the Polio Endgame: A Review. Abstract: In May 2016, countries using oral polio vaccine for routine immunization switched from trivalent oral poliovirus vaccine (tOPV) to bivalent type …
Case report of bursitis and bone erosion caused by the DTP vaccine.
PMID: Vaccine. 2015 Nov 17 ;33(46):6152-5. Epub 2015 Oct 11. PMID: 26458794 Abstract Title: Bone erosion and subacromial bursitis caused by diphtheria-tetanus-poliomyelitis vaccine. Abstract: Revaxis(®) is a vaccine against diphtheria, tetanus and poliomyelitis (dT-IPV). This vaccine should not be administered by the intradermal or intravenous route. Poor injection techniques and related consequences are rare. We …
Continue reading “Case report of bursitis and bone erosion caused by the DTP vaccine.”
Attentuated Sabin poliovirus strains are being developed due to the chances that the current highly virulent strain may be released from production facilities. However, it’s well-known that Sabin strains may revert to paralytic strains.
PMID: PLoS Pathog. 2015 Dec ;11(12):e1005316. Epub 2015 Dec 31. PMID: 26720150 Abstract Title: New Strains Intended for the Production of Inactivated Polio Vaccine at Low-Containment After Eradication. Abstract: Poliomyelitis has nearly been eradicated through the efforts of the World Health Organization's Global Eradication Initiative raising questions on containment of the virus after it has …
Replacement of OPV with IPV could translate to approximately 4000 deaths for each case of vaccine-associated paralytic poliomyelitis prevented, and might cause more than 300,000 additional deaths each year.
PMID: Lancet. 2016 Mar 12 ;387(10023):1054-1055. PMID: 27025182 Abstract Title: Changing oral vaccine to inactivated polio vaccine might increase mortality. Abstract: [n/a] read more
It remains to be assessed whether IPV has non-specific effects and especially whether IPV could be detrimental for child health.
PMID: Lancet Infect Dis. 2016 Apr ;16(4):410. PMID: 27036345 Abstract Title: Is introduction of IPV"Good news for billions of children"?–Author's reply. Abstract: [n/a] read more
Further evidence of poorly designed vaccine clinical trials to investigate safety.
PMID: Vaccine. 2016 07 19 ;34(33):3810-6. Epub 2016 Jun 18. PMID: 27288217 Abstract Title: A Phase III randomized, double-blind, clinical trial of an investigational hexavalent vaccine given at 2, 4, and 11-12 months. Abstract: BACKGROUND: Combination vaccines simplify vaccination visits and improve coverage and timeliness. DTaP5-HB-IPV-Hib is a new investigational, fully-liquid, combination vaccine designed to …
Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells.
PMID: Toxicol Ind Health. 2019 Oct ;35(10):670-678. Epub 2019 Oct 10. PMID: 31601156 Abstract Title: Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells through activating TLR-mediated pathway. Abstract: This study aims to investigate the role of Toll-like receptors (TLRs) on fine particulate matter (PM)-induced inflammatory responses of vascular endothelial cells. Inflammatory factors …
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