PMID: Vaccine. 2016 12 7 ;34(50):6172-6180. Epub 2016 Nov 10. PMID: 27840013 Abstract Title: Simultaneous vaccination with MMR and DTaP-IPV-Hib and rate of hospital admissions with any infections: A nationwide register based cohort study. Abstract: BACKGROUND: In Denmark, live measles, mumps, and rubella vaccine (MMR) is associated with a reduced risk of infectious disease admissions, …
Author Archives: Taylor Mercado
Fine particle environmental pollution and cardiovascular diseases.
PMID: Metabolism. 2019 Nov ;100S:153944. PMID: 31610849 Abstract Title: Fine particle environmental pollution and cardiovascular diseases. Abstract: Air pollution affects 90% of the world's population and has caused 9 million deaths in 2015, becoming the most important cause of premature deaths in the world. Exposure to fine particulate matter, a major component of urban air …
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The impact of inhaled ambient ultrafine particulate matter on developing brain: potential importance of elemental contaminants.
PMID: Toxicol Pathol. 2019 Dec ;47(8):976-992. Epub 2019 Oct 14. PMID: 31610749 Abstract Title: The Impact of Inhaled Ambient Ultrafine Particulate Matter on Developing Brain: Potential Importance of Elemental Contaminants. Abstract: Epidemiological studies report associations between air pollution (AP) exposures and several neurodevelopmental disorders including autism, attention deficit disorder, and cognitive delays. Our studies in …
Sabin vaccine strains are genetically unstable and can revert to a virulent transmissible form.
PMID: PLoS Pathog. 2017 01 ;13(1):e1006117. Epub 2017 Jan 19. PMID: 28103317 Abstract Title: Genetically Thermo-Stabilised, Immunogenic Poliovirus Empty Capsids; a Strategy for Non-replicating Vaccines. Abstract: While wild type polio has been nearly eradicated there will be a need to continue immunisation programmes for some time because of the possibility of re-emergence and the existence …
Particulate matter was significantly associated with a higher risk of nasopharyngeal cancer in Taiwanese men.
PMID: J Investig Med. 2019 Oct 16. Epub 2019 Oct 16. PMID: 31619486 Abstract Title: Association between coarse particulate matter (PM) and nasopharyngeal carcinoma among Taiwanese men. Abstract: The nasopharyngeal tract traps mainly coarse particles in inhaled air. Soluble carcinogenic compounds, endotoxins, and trace metals contained in these particles are potential causes of inflammation and …
Amoebic dysentery and bronchiolitis were reported serious adverse events in an inactivated polio vaccine trial.
PMID: Lancet Infect Dis. 2017 07 ;17(7):745-753. Epub 2017 Apr 25. PMID: 28454674 Abstract Title: Immunogenicity and safety of three aluminium hydroxide adjuvanted vaccines with reduced doses of inactivated polio vaccine (IPV-Al) compared with standard IPV in young infants Abstract: BACKGROUND: Cost and supply constraints are key challenges in the use of inactivated polio vaccine …
Developmental impact of air pollution on brain function.
PMID: Neurochem Int. 2019 Dec ;131:104580. Epub 2019 Oct 15. PMID: 31626830 Abstract Title: Developmental impact of air pollution on brain function. Abstract: Air pollution is an important contributor to the global burden of disease, particularly to respiratory and cardiovascular diseases. In recent years, evidence is accumulating that air pollution may adversely affect the nervous …
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The trivalent oral polio vaccine has transitioned to the bivalent oral polio vaccine only to be replaced by a trivalent inactivated polio virus to “protect against” vaccine-induced type 2 poliovirus.
PMID: Clin Infect Dis. 2017 Sep 1 ;65(5):851-854. PMID: 28444156 Abstract Title: The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb. Abstract: The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the …
Air pollution is associated with dysregulation of glucose metabolism.
PMID: Environ Res. 2020 Jan ;180:108817. Epub 2019 Oct 12. PMID: 31627156 Abstract Title: Ambient air pollution and diabetes: A systematic review and meta-analysis. Abstract: BACKGROUND: Air pollutants are suggested to be related to type 2 diabetes (T2D). Since several high quality papers on air pollutants and T2D have been published beyond the last reviews, …
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IPV requires a much higher standard for biosafety and other containment requirements, because IPV uses virulent poliovirus strains as raw material.
PMID: J Infect Dis. 2019 Oct 8 ;220(10):1551-1557. PMID: 30958543 Abstract Title: Immunogenicity and Safety of a Sabin Strain-Based Inactivated Polio Vaccine: A Phase 3 Clinical Trial. Abstract: BACKGROUND: The Sabin strain-based inactivated polio vaccine (sIPV) plays a vital role in eradicating poliomyelitis in developing countries.METHODS: The study was designed as a randomized, controlled, double-blinded, …
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