Polyphenol extracts from three colombian passion fruits prevent inflammation-induced barrier dysfunction of caco-2 cells.

PMID:  Molecules. 2019 Dec 17 ;24(24). Epub 2019 Dec 17. PMID: 31861064 Abstract Title:  Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells. Abstract:  Chronic intestinal inflammation is associated with pathophysiology of obesity and inflammatory bowel diseases. Gastrointestinal inflammation increases barrier dysfunction exacerbating the immune response and perpetuating chronic …

The structure features and improving effects of polysaccharide from Astragalus membranaceus on antibiotic-associated diarrhea.

PMID:  Antibiotics (Basel). 2019 Dec 23 ;9(1). Epub 2019 Dec 23. PMID: 31877915 Abstract Title:  The Structure Features and Improving Effects of Polysaccharide fromon Antibiotic-Associated Diarrhea. Abstract:  () is often used as a medical and food resource in China. The present study was designed to investigate the features and effects of polysaccharide from(WAP) on rats …

Astragaloside IV protects against diabetic nephropathy.

PMID:  BMC Complement Altern Med. 2019 Dec 5 ;19(1):355. Epub 2019 Dec 5. PMID: 31805910 Abstract Title:  Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats. Abstract:  BACKGROUND: Astragaloside IV (AS-IV) was reported to play a role in improving diabetic nephropathy (DN), however, the underlying mechanisms still remain unclear. The aim …

Astragaloside IV protects against oxidative stress in calf small intestine epithelial cells.

PMID:  Int J Mol Sci. 2019 Dec 5 ;20(24). Epub 2019 Dec 5. PMID: 31817362 Abstract Title:  Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling. Abstract:  Oxidative stress can damage intestinal epithelial cell integrity and function, causing gastrointestinal disorders. Astragaloside IV (ASIV) exhibits a variety of …

Astragaloside IV reverses simvastatin-induced skeletal muscle injury.

PMID:  Phytother Res. 2019 Dec 10. Epub 2019 Dec 10. PMID: 31823428 Abstract Title:  Astragaloside IV reverses simvastatin-induced skeletal muscle injury by activating the AMPK-PGC-1α signalling pathway. Abstract:  In this study, we investigated the effect of astragaloside IV on skeletal muscle energy metabolism disorder caused by statins and explored the possible mechanisms. High-fat diet-fed apolipoprotein …

Astragaloside IV alleviates cerebral ischemia-reperfusion injury.

PMID:  Pharmacology. 2019 Dec 11:1-9. Epub 2019 Dec 11. PMID: 31825924 Abstract Title:  Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the Janus Kinase 2 and Signal Transducer and Activator of Transcription 3 Signaling Pathway. Abstract:  Astragaloside IV (AS-IV) is an active component extracted from the traditional Chinese herbal medicine. AS-IV is a neuroprotective component …

Astragaloside IV exerts cardioprotection in animal models of viral myocarditis.

PMID:  Front Pharmacol. 2019 ;10:1388. Epub 2019 Nov 28. PMID: 31849654 Abstract Title:  Astragaloside IV Exerts Cardioprotection in Animal Models of Viral Myocarditis: A Preclinical Systematic Review and Meta-Analysis. Abstract:  Astragaloside IV (AS-IV), the essential active component of astragalus, possesses diverse biological activities that have beneficial effects against cardiovascular disease. Here, we conducted a preclinical …

Astragaloside IV attenuates sepsis-induced intestinal barrier dysfunction.

PMID:  Int Immunopharmacol. 2019 Dec 9 ;78:106066. Epub 2019 Dec 9. PMID: 31835087 Abstract Title:  Astragaloside IV attenuates sepsis-induced intestinal barrier dysfunction via suppressing RhoA/NLRP3 inflammasome signaling. Abstract:  Intestinal barrier dysfunction is a trigger for sepsis progression. NLRP3 inflammasome and RhoA contribute to sepsis and intestinal inflammation. The current study aimed to explore the effects …

Tetramethylpyrazine attenuates blood-brain barrier disruption in ischemia/reperfusion injury through the JAK/STAT signaling pathway.

PMID:  Eur J Pharmacol. 2019 Jul 5 ;854:289-297. Epub 2019 Apr 17. PMID: 31004602 Abstract Title:  Tetramethylpyrazine attenuates blood-brain barrier disruption in ischemia/reperfusion injury through the JAK/STAT signaling pathway. Abstract:  Tetramethylpyrazine (TMP) has been studied in depth and is widely used in the treatment of many kinds of diseases in China. However, whether it has …

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