Melatonin might be a therapeutic option for helping patients suffering from diabetes and contributed to Alzheimer’s disease.

PMID:  Neurochem Int. 2020 Jan ;132:104601. Epub 2019 Nov 12. PMID: 31726088 Abstract Title:  Melatonin attenuates streptozotocin-induced Alzheimer-like features in hyperglycemic rats. Abstract:  Diabetes mellitus (DM) is increasingly recognized as a risk for developing of Alzheimer's disease (AD). Accordingly, it has been reported that melatonin level is disturbed in both DM and AD which indicates …

Melatonin ameliorates the drug induced nephrotoxicity.

PMID:  Nefrologia. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31735377 Abstract Title:  Melatonin ameliorates the drug induced nephrotoxicity: Molecular insights. Abstract:  BACKGROUND: Drug-induced nephrotoxicity is a frequent adverse event that can lead to acute or chronic kidney disease and increase the healthcare expenditure. It has high morbidity and mortality incidence in 40-70% of renal …

Melatonin protects against Epirubicin-induced ovarian damage.

PMID:  J Reprod Dev. 2019 Nov 15. Epub 2019 Nov 15. PMID: 31735743 Abstract Title:  Melatonin protects against Epirubicin-induced ovarian damage. Abstract:  One major side effect of chemotherapy that young women with cancer suffer from is ovarian damage. Therefore, it is necessary to study the pathogenesis of chemotherapeutic drugs in order to develop pharmaceutical agents …

Melatonin can be considered a potential therapeutic agent to attenuate the metabolic and inflammatory disorders triggered by obesity.

PMID:  Front Endocrinol (Lausanne). 2019 ;10:750. Epub 2019 Nov 5. PMID: 31749764 Abstract Title:  Melatonin Supplementation Decreases Hypertrophic Obesity and Inflammation Induced by High-Fat Diet in Mice. Abstract:  Obesity results from critical periods of positive energy balance characterized by caloric intake greater than energy expenditure. This disbalance promotes adipose tissue dysfunction which is related to …

Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos.

PMID:  J Pineal Res. 2019 Nov 27:e12627. Epub 2019 Nov 27. PMID: 31773776 Abstract Title:  Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos. Abstract:  Melatonin, a major hormone of the pineal gland, exerts many beneficial effects on mitochondria. Several studies have shown that melatonin can protect against toxin-induced oocyte …

Melatonin stimulates epithelium migration in wound models In vitro and In vivo.

PMID:  Bull Exp Biol Med. 2019 Dec ;168(2):242-246. Epub 2019 Nov 27. PMID: 31776954 Abstract Title:  Melatonin Stimulates Epithelium Migration in Wound Models In Vitro and In Vivo. Abstract:  We studied the effect of bovine brain gangliosides, individual ganglioside GM1, and melatonin on the rate of wound closure under in vitro conditions and the effect …

Melatonin inhibits inflammasome-associated activation of endothelium and macrophages attenuating pulmonary arterial hypertension.

PMID:  Cardiovasc Res. 2019 Nov 27. Epub 2019 Nov 27. PMID: 31774487 Abstract Title:  Melatonin inhibits inflammasome-associated activation of endothelium and macrophages attenuating pulmonary arterial hypertension. Abstract:  AIM: Pulmonary arterial hypertension (PAH) is a pathophysiological syndrome associated with pulmonary/systemic inflammation. Melatonin relieves PAH, but the molecular mode of action remains unclear. Here, we investigated the …

Exposure of E. coli DH5α to Wi-Fi radiofrequency radiation for 5 hours influenced several bacterial cellular and metabolic processes.

PMID:  Sci Rep. 2019 Oct 8 ;9(1):14425. Epub 2019 Oct 8. PMID: 31595026 Abstract Title:  Global gene expression analysis of Escherichia coli K-12 DH5α after exposure to 2.4 GHz wireless fidelity radiation. Abstract:  This study investigated the non-thermal effects of Wi-Fi radiofrequency radiation of 2.4 GHz on global gene expression in Escherichia coli K-12 DH5α. High-throughput RNA-sequencing …

Wi-Fi could increase antibiotic resistance and motility of E.coli 0157H7, as well as enhancing biofilm formation by E.coli 0157H7, S.aureus and S. epidermis.

PMID:  J Biomed Phys Eng. 2019 Oct ;9(5):579-586. Epub 2019 Oct 1. PMID: 31750272 Abstract Title:  Evaluation of Wi-Fi Radiation Effects on Antibiotic Susceptibility, Metabolic Activity and Biofilm Formation by Escherichia0157H7,and. Abstract:  Background: The radiation emitted from electromagnetic fields (EMF) can cause biological effects on prokaryotic and eukaryotic cells, including non-thermal effects.Objective: The present study …

Wi-Fi reduced anticonvulsive and antioxidant effect of melatonin.

PMID:  Pathophysiology. 2019 Nov 21. Epub 2019 Nov 21. PMID: 31785933 Abstract Title:  Wi-Fi decreases melatonin protective effect and increases hippocampal neuronal damage in pentylenetetrazole induced model seizures in rats. Abstract:  AIM: Epilepsy is a common brain disorder in which the seizures could cause a neuronal loss in the hippocampus. Oxidative stress has an important …

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