PMID: Med Hypotheses. 2019 Nov 27 ;136:109513. Epub 2019 Nov 27. PMID: 31812013 Abstract Title: Could PCSK9 be a new therapeutic target of Eugenol? In vitro and in silico evaluation of hypothesis. Abstract: PCSK9 (Proprotein convertase Subtilisin/Kexin Type 9), an important regulator of lipid metabolism, has been shown to play a role in hepatocellular carcinoma …
Continue reading “PCSK9 could therapeutically be targeted by eugenol in leukemia cells.”
PMID: Cell Mol Neurobiol. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31828466 Abstract Title: Berberine attenuated the cytotoxicity induced by t-BHP via inhibiting oxidative stress and mitochondria dysfunction in PC-12 cells. Abstract: Neurodegenerative diseases all share several common features such as involvement of oxidative damage and mitochondrial dysfunction in pathogenesis. Oxidative stress induced by …
PMID: PLoS One. 2019 ;14(12):e0225660. Epub 2019 Dec 16. PMID: 31841506 Abstract Title: Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments. Abstract: The treatment of glioblastoma is challenging for the clinician, due to its chemotherapeutic resistance. …
PMID: Biomed Pharmacother. 2019 Jul ;115:108900. Epub 2019 May 1. PMID: 31054510 Abstract Title: Antidepressant-like effects of ginseng fruit saponin in myocardial infarction mice. Abstract: BACKGROUND: Recently, the development of cardiovascular disease (CVD) has been proved to be closely associated with depression in which 5-HT plays a crucial role. Ginseng Fruit Saponin (GFS) and Metoprolol …
The U.S. Food and Drug Administration (FDA) recently announced a new guidance that could lead to the end of homeopathy in America in less than three months
PMID: J Ginseng Res. 2019 Oct ;43(4):606-617. Epub 2018 Aug 10. PMID: 31695567 Abstract Title: Hepatoprotective effect of ultrasonicated ginseng berry extract on a rat mild bile duct ligation model. Abstract: Background: Theberry extract (GBE) is well known to have an antidiabetic effect. The aim of this study is to evaluate and investigate the protective …
PMID: Exp Ther Med. 2019 Dec ;18(6):4388-4396. Epub 2019 Oct 8. PMID: 31772634 Abstract Title: Ginseng berry aqueous extract prevents scopolamine-induced memory impairment in mice. Abstract: Ginseng berry exhibits a diverse range of pharmacological activities. The present study aimed to examine the neuroprotective effects of ginseng berry aqueous extract (GBE) against oxidative stress and to …
PMID: Molecules. 2019 Dec 9 ;24(24). Epub 2019 Dec 9. PMID: 31835292 Abstract Title: Review of Ginseng Anti-Diabetic Studies. Abstract: Ginseng is one of the most valuable and commonly used Chinese medicines not only in ancient China but also worldwide. Ginsenosides, also known as saponins or triterpenoids, are thought to be responsible for the beneficial …
PMID: BMC Res Notes. 2019 Dec 12 ;12(1):805. Epub 2019 Dec 12. PMID: 31831054 Abstract Title: Lycopene improves on basic hematological and immunological parameters in diabetes mellitus. Abstract: OBJECTIVE: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the …
PMID: Neurochem Res. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31728856 Abstract Title: Role of Oxidative Stress, MAPKinase and Apoptosis Pathways in the Protective Effects of Thymoquinone Against Acrylamide-Induced Central Nervous System Toxicity in Rat. Abstract: The present study evaluated biochemical endpoints characterizing acrylamide (ACR) neurotoxicity in the cortex of rats, following the possible …
Continue reading “Thymoquinone protected against acrylamide-mediated neurotoxicity.”
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