PMID: Nutr Res. 2019 Oct 24 ;73:58-66. Epub 2019 Oct 24. PMID: 31841748 Abstract Title: Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo. Abstract: Obesity-induced chronic inflammation in adipose tissue plays a critical role in the development of insulin …
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Mid infrared light treatment attenuates cognitive decline and alters the gut microbiota community.
PMID: Biochem Biophys Res Commun. 2019 Dec 9. Epub 2019 Dec 9. PMID: 31831179 Abstract Title: Mid infrared light treatment attenuates cognitive decline and alters the gut microbiota community in APP/PS1 mouse model. Abstract: Alzheimer's disease (AD) as the first most neurodegenerative disease in the elderly still has no effective therapy, suggesting that the intervention …
Commiphora myrrha inhibits itch-associated histamine and IL-31 production in stimulated mast cells.
PMID: Exp Ther Med. 2019 Sep ;18(3):1914-1920. Epub 2019 Jul 1. PMID: 31410154 Abstract Title: inhibits itch-associated histamine and IL-31 production in stimulated mast cells. Abstract: (Myrrh) is widely recognized for its anti-inflammatory and antimicrobial properties, which are utilized for the treatment of oral ulcers, gingivitis, sinusitis, glomerulonephritis, brucellosis and a variety of skin disorders. …
Guggulipid ameliorates adjuvant-induced arthritis and liver oxidative damage
PMID: Phytomedicine. 2019 Nov ;64:152924. Epub 2019 Apr 9. PMID: 31465983 Abstract Title: Guggulipid ameliorates adjuvant-induced arthritis and liver oxidative damage by suppressing inflammatory and oxidative stress mediators. Abstract: BACKGROUND: Arthritis is a common degenerative joint disease characterized by deterioration of articular cartilage, subchondral bone, and associated with immobility, pain and inflammation. The incessant action …
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The anti-diabetic and antioxidant effects of a combination of Commiphora mukul, Commiphora myrrha and Terminalia chebula in diabetic rats.
PMID: Avicenna J Phytomed. 2019 Sep-Oct;9(5):454-464. PMID: 31516859 Abstract Title: The anti-diabetic and antioxidant effects of a combination of,andin diabetic rats. Abstract: Objective: Effects ofandethanolic extracts andhydro-ethanolic extract combination were evaluated in streptozotocin (STZ)-induced diabetic rats.Materials and Methods: Male Wistar rats (n=48) were randomly assigned into: control; diabetic; diabetic+metformin (300 mg/kg); diabetic+dose 1 of herbal …
Virucidal effect of guggulsterone isolated from commiphora gileadensis.
PMID: Planta Med. 2019 Nov ;85(16):1225-1232. Epub 2019 Oct 7. PMID: 31590195 Abstract Title: Virucidal Effect of Guggulsterone Isolated from Commiphora gileadensis. Abstract: , locally known as becham, is a plant used in traditional Arabian medicine for treating headache, constipation, stomach, joint pain, and inflammatory disorders. Several studies have reported its antibacterial properties; however, no …
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These results demonstrated that Hnk may be of value as a cardioprotective drug by inhibiting cardiomyocyte senescence.
PMID: Int J Mol Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31746354 Abstract Title: Honokiol antagonizes doxorubicin‑induced cardiomyocyte senescence by inhibiting TXNIP‑mediated NLRP3 inflammasome activation. Abstract: Senescence of cardiomyocytes is considered a key factor for the occurrence of doxorubicin (Dox)‑associated cardiomyopathy. The NOD‑like receptor family pyrin domain‑containing 3 (NLRP3) inflammasome is reported to be …
Honokiol is a potential therapeutic agent and has a synergistic effect with 5-FU in human urothelial cell carcinoma cells.
PMID: Anticancer Res. 2019 Dec ;39(12):6555-6565. PMID: 31810921 Abstract Title: Honokiol Is a Potential Therapeutic Agent and Has a Synergistic Effect With 5-FU in Human Urothelial Cell Carcinoma Cells. Abstract: BACKGROUND/AIM: Honokiol is a biphenolic component of the bark of Magnolia, and has been shown to exert several activities, including anti-depressant, anti-emetic, anti-oxidative, anti-thrombotic, anti-angiogenesis, …
Honokiol enhances TRAIL-mediated apoptosis through STAMBPL1-induced survivin and c-FLIP degradation.
PMID: Biomolecules. 2019 Dec 6 ;9(12). Epub 2019 Dec 6. PMID: 31817770 Abstract Title: Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation. Abstract: Honokiol is a natural biphenolic compound extracted from traditional Chinese medicinespecies, which have been known to display various biological effects including anti-cancer, anti-proliferative, anti-angiogenic, and anti-metastatic activities in cancer cells. …
Antimicrobial activity of eugenol against carbapenem-resistant Klebsiella pneumoniae and its effect on biofilms.
PMID: Microb Pathog. 2019 Dec 11 ;139:103924. Epub 2019 Dec 11. PMID: 31837416 Abstract Title: Antimicrobial activity of eugenol against carbapenem-resistant Klebsiella pneumoniae and its effect on biofilms. Abstract: A preliminary study found that eugenol expressed an antibacterial activity against Klebsiella pneumoniae. However, the mechanism of action of eugenol against K. pneumoniae still remains unexplored. …
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