Category Archives: Uncategorized

PMID:  Nutr Metab Cardiovasc Dis. 2019 Sep 30. Epub 2019 Sep 30. PMID: 31791634 Abstract Title:  Grape seed procyanidin suppresses inflammation in cigarette smoke-exposed pulmonary arterial hypertension rats by the PPAR-γ/COX-2 pathway. Abstract:  BACKGROUND AND AIM: Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling, which is mainly caused by inflammation. Inhibiting inflammation can …

Continue reading “Grape seed procyanidin suppresses inflammation caused by cigarette smoke.”

n/a PMID:  Aust Endod J. 2019 Dec 8. Epub 2019 Dec 8. PMID: 31814249 Abstract Title:  Antimicrobial effectiveness of grape seed extract against Enterococcus faecalis biofilm: A Confocal Laser Scanning Microscopy analysis. Abstract:  This study evaluated the antimicrobial effectiveness of 6.5% Vitis vinifera grape seed extract (GSE) against Enterococcus faecalis biofilm using confocal laser scanning …

Continue reading “Antimicrobial effectiveness of grape seed extract against Enterococcus faecalis biofilm.”

PMID:  J Food Biochem. 2019 Aug ;43(8):e12962. Epub 2019 Jun 28. PMID: 31368542 Abstract Title:  The plant flavonoid, fisetin alleviates cigarette smoke-induced oxidative stress, and inflammation in Wistar rat lungs. Abstract:  In the present study, we tested the antioxidant and anti-inflammatory potential of the plant flavonoid, fisetin against cigarette smoke-induced oxidative stress, and inflammation in …

Continue reading “Fisetin alleviates cigarette smoke-induced oxidative stress and lung inflammation.”

PMID:  Biofactors. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31634424 Abstract Title:  Fisetin, a phytopolyphenol, targets apoptotic and necroptotic cell death in HepG2 cells. Abstract:  Fisetin (3,7,3',4'-tetrahydroxyflavone), a bioactive dietary flavonoid, intrigued scientists for its anticancer potential against various cancer types. We investigated the fisetin-induced inhibition of growth and survival of human hepatocellular carcinoma. …

Continue reading “Fiestin has potential as a therapeutic agent against hepatocellular carcinoma.”

PMID:  Int Heart J. 2019 Nov 30 ;60(6):1398-1406. Epub 2019 Oct 31. PMID: 31666455 Abstract Title:  Fisetin Alleviates Atrial Inflammation, Remodeling, and Vulnerability to Atrial Fibrillation after Myocardial Infarction. Abstract:  Atrial inflammation and fibrosis are the critical processes involved in atrial fibrillation (AF) after myocardial infarction (MI). Fisetin is a dietary flavonoid that has shown …

Continue reading “Fisetin alleviates atrial inflammation, remodelling, and vulnerability to atrial fibrillation after myocardial infarction.”

PMID:  J Nutr Biochem. 2019 Nov 25 ;77:108253. Epub 2019 Nov 25. PMID: 31835147 Abstract Title:  Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction by regulation of multicombined signaling. Abstract:  Excess high-fat diet (HFD) intake predisposes the occurrence of obesity-associated heart injury, but the mechanism is elusive. Fisetin (FIS), as a natural flavonoid, …

Continue reading “Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction.”

PMID:  Curr Microbiol. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31807847 Abstract Title:  Effect of Black Grape Seed Extract (Vitis vinifera) on Biofilm Formation of Methicillin-Resistant Staphylococcus aureus and Staphylococcus haemolyticus. Abstract:  Grape seeds are considered one of the most important sources for phenolic and other compounds and is globally consumed for the biological …

Continue reading “This report confirms the antibacterial activity of the methanolic extract of the black grape seeds.”

PMID:  Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31832973 Abstract Title:  Gallic Acid Attenuated LPS-Induced Neuroinflammation: Protein Aggregation and Necroptosis. Abstract:  Gallic acid (3,4,5-trihydroxybenzoic acid, GA), a phenolic acid, is ubiquitous in almost all parts of the plant. In the present study, a neuroinflammatory rat model using intranigral infusion of lipopolysaccharides (LPS, …

Continue reading “Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.”

PMID:  Foods. 2019 Aug 21 ;8(9). Epub 2019 Aug 21. PMID: 31438605 Abstract Title:  Interaction Mechanism of Flavonoids andα-Glucosidase: Experimental and Molecular Modelling Studies. Abstract:  Flavonoids are known to play a role in hypoglycemia by inhibitingα-glucosidase. However, their interaction mechanism with α-glucosidase still needs to be elaborated. In this study, the α-glucosidase inhibitory activities of …

Continue reading “Interaction mechanism of flavonoids and α-glucosidase.”

PMID:  Colloids Surf B Biointerfaces. 2019 Nov 11 ;186:110640. Epub 2019 Nov 11. PMID: 31835184 Abstract Title:  Myricetin inhibits amyloid fibril formation of globular proteins by stabilizing the native structures. Abstract:  Myricetin has been identified as a naturally occurring flavonoid class of polyphenolic compound which shows multiple medical benefits including antidiabetic, anticancerous and antioxidant properties. …

Continue reading “Myricetin inhibits amyloid fibril formation of globular proteins by stabilizing the native structures.”