PMID: Mol Cell Endocrinol. 2016 10 15 ;434:135-43. Epub 2016 Jun 27. PMID: 27364889 Abstract Title: Betulinic acid ameliorates experimental diabetic-induced renal inflammation and fibrosis via inhibiting the activation of NF-κB signaling pathway. Abstract: Diabetic nephropathy (DN) is the leading cause of end-stage renal failure and is characterized by excessive deposition of extracellular matrix (ECM) …
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Protective effect of betulinic acid on early atherosclerosis.
PMID: Eur J Pharmacol. 2017 Feb 5 ;796:224-232. Epub 2016 Nov 26. PMID: 27894808 Abstract Title: Protective effect of betulinic acid on early atherosclerosis in diabetic apolipoprotein-E gene knockout mice. Abstract: Atherosclerosis, a chronic and progressive disease, is a leading cause of endothelial dysfunction, diabetes mellitus, hypertension, and hypercholesterolemia. Betulinic acid (BA), a pentacyclic triterpene, …
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Betulinic acid and the pharmacological effects of tumor suppression.
PMID: Mol Med Rep. 2016 Nov ;14(5):4489-4495. Epub 2016 Oct 4. PMID: 27748864 Abstract Title: Betulinic acid and the pharmacological effects of tumor suppression (Review). Abstract: Betulinic acid (BA), a lupane-type pentacyclic triterpenoid saponin from tree bark, has the potential to induce the apoptosis of cancer cells without toxicity towards normal cells in vitro and in vivo. …
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Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny.
PMID: Sci Rep. 2019 Dec 2 ;9(1):18029. Epub 2019 Dec 2. PMID: 31792261 Abstract Title: Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny. Abstract: Exposure to bisphenol A (BPA) has been related to male reproductive disorders. Since this endocrine disruptor also displays genotoxic and …
Oral exposure to low dose bisphenol A aggravates allergic airway inflammation.
PMID: Toxicol Rep. 2019 ;6:1253-1262. Epub 2019 Nov 17. PMID: 31788436 Abstract Title: Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice. Abstract: Bisphenol A (BPA) is widely used in many consumer products and has adverse effects on human health including allergic diseases. We investigated the effects of low dose BPA, …
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Studies on the phytomodulatory potential of fenugreek on bisphenol-A induced testicular damage.
PMID: Andrologia. 2019 Dec 3:e13492. Epub 2019 Dec 3. PMID: 31793690 Abstract Title: Studies on the phytomodulatory potential of fenugreek (Trigonella foenum-graecum) on bisphenol-A induced testicular damage in mice. Abstract: Bisphenol A (BPA), an organic synthetic compound and endocrine disruptor, which majorly cause deleterious effects on male reproductory system. Fenugreek (Trigonella foenum-graecum), associated with Leguminosae …
Cytotoxic activity of caffeic acid and gallic acid against MCF-7 human breast cancer cells.
PMID: Avicenna J Phytomed. 2019 Nov-Dec;9(6):574-586. PMID: 31763216 Abstract Title: Cytotoxic activity of caffeic acid and gallic acid against MCF-7 human breast cancer cells: Anandstudy. Abstract: Objective: Phenolic compounds have been considered inhibitors of various cancers.Material and Methods: In this study, caffeic acid and gallic acid were appraised for their possible effects on apoptotic genes …
Acute caffeine supplementation is highly ergogenic for movement velocity in resistance exercise.
PMID: Sports Med. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31643020 Abstract Title: Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis. Abstract: BACKGROUND: Several studies investigated the effects of caffeine supplementation on movement velocity in resistance exercise. However, these studies presented inconsistent findings.OBJECTIVE: This paper aimed …
Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma.
PMID: Med Oncol. 2019 Oct 29 ;36(12):97. Epub 2019 Oct 29. PMID: 31664534 Abstract Title: Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma. Abstract: The development of drug resistance affecting the prognosis of patients with hepatocellular carcinoma (HCC) leads to low survival rate of HCC …
An association between vaccines and autoimmune diseases cannot be ruled out.
PMID: Eur J Dermatol. 2004 Mar-Apr;14(2):86-90. PMID: 15196997 Abstract Title: Autoimmune diseases and vaccinations. Abstract: The potential association between vaccination and autoimmune diseases has been largely questioned in the past few years, but this assumption has mostly been based on case reports. The available evidence derived from several negative epidemiological studies is reassuring and at …
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