PMID: Oxid Med Cell Longev. 2019 ;2019:8781690. Epub 2019 Aug 19. PMID: 31531187 Abstract Title: Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Abstract: Targeting aberrant metabolism is a promising strategy for inhibiting cancer growth and metastasis. Research is now geared towards investigating the inhibition of glycolysis for …
Category Archives: Uncategorized
Anti-inflammatory effect and potential mechanism of betulinic acid on λ-carrageenan-induced paw edema in mice.
PMID: Biomed Pharmacother. 2019 Oct ;118:109347. Epub 2019 Aug 16. PMID: 31545273 Abstract Title: Anti-inflammatory effect and potential mechanism of betulinic acid onλ-carrageenan-induced paw edema in mice. Abstract: λ-Carrageenan (Carr), a seaweed polysaccharide, is used as a proinflammatory agent in research. Betulinic acid (BA), a naturally occurring pentacyclic triterpenoid, exerts immunomodulatory, antioxidant, anti-inflammatory, antitumor, anti-malarial …
Betulinic acid attenuates T-2-toxin-induced testis oxidative damage.
PMID: Biomolecules. 2019 Nov 26 ;9(12). Epub 2019 Nov 26. PMID: 31779213 Abstract Title: Betulinic Acid Attenuates T-2-Toxin-Induced Testis Oxidative Damage Through Regulation of the JAK2/STAT3 Signaling Pathway in Mice. Abstract: T-2 toxin is one of the most toxic type A trichothecene mycotoxins in nature, and it exhibits reproductive toxicity. Betulinic acid (BA) is a …
Continue reading “Betulinic acid attenuates T-2-toxin-induced testis oxidative damage.”
A natural compound from Wasabia japonica inhibited the viability of human chronic myelogenous leukemia K562 cells.
PMID: Biomolecules. 2019 Nov 23 ;9(12). Epub 2019 Nov 23. PMID: 31771225 Abstract Title: Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate Induces Cell Death with Coexisting Mitotic Arrest and Autophagy in Human Chronic Myelogenous Leukemia K562 Cells. Abstract: A natural compound from, 6-(methylsulfinyl) hexyl isothiocyanate (6-MITC) was investigated for its anti-leukemia activity and mechanism of action. It …
These results support Photobiomodulation as a successful neuroprotective therapy against the inflammatory component of early Parkinson’s disease.
PMID: Biomolecules. 2019 Aug 19 ;9(8). Epub 2019 Aug 19. PMID: 31430990 Abstract Title: Effect of Photobiomodulation in Rescuing Lipopolysaccharide-Induced Dopaminergic Cell Loss in the Male Sprague-Dawley Rat. Abstract: Photobiomodulation (PBM) provides neuroprotection against dopaminergic cell death and associated motor deficits in rodent and primate models of Parkinson's disease (PD). However, it has not yet …
Transcranial photobiomodulation might be a promising therapeutic target for preventing or delaying Alzheimer’s disease.
PMID: Biomed Opt Express. 2019 Aug 1 ;10(8):4003-4017. Epub 2019 Jul 15. PMID: 31452991 Abstract Title: Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer's disease. Abstract: In this pilot study, we analyzed effects of transcranial photobiomodulation (tPBM, 1267 nm, 32 J/cm) on …
Laser can be a therapy of choice in the treatment of pressure ulcers.
PMID: Photochem Photobiol. 2019 Sep 24. Epub 2019 Sep 24. PMID: 31550398 Abstract Title: Effect of Photobiomodulation on Repairing Pressure Ulcers in Adult and Elderly Patients: A Systematic Review. Abstract: Evaluation of photobiomodulation therapy (PBMT) in the treatment of pressure ulcers in adults and the elderly. Systematic review, based on the recommendations of the handbook, proposed …
Continue reading “Laser can be a therapy of choice in the treatment of pressure ulcers.”
Photobiomodulation has a potential role in reducing cartilage degradation and long-term central sensitization associated with chronic osteoarthritis.
PMID: Cartilage. 2019 Sep 30:1947603519876338. Epub 2019 Sep 30. PMID: 31569995 Abstract Title: Photobiomodulation Therapy Partially Restores Cartilage Integrity and Reduces Chronic Pain Behavior in a Rat Model of Osteoarthritis: Involvement of Spinal Glial Modulation. Abstract: OBJECTIVE: Chronic pain associated with osteoarthritis (OA) often leads to reduced function and engagement in activities of daily living. …
Photobiomodulation therapy in knee osteoarthritis reduces oxidative stress and inflammatory cytokines.
PMID: J Biophotonics. 2019 Sep 30:e201900204. Epub 2019 Sep 30. PMID: 31568634 Abstract Title: Photobiomodulation therapy in knee osteoarthritis reduces oxidative stress and inflammatory cytokines in rats. Abstract: Knee osteoarthritis (OA) is a chronic disease that causes pain and gradual degeneration of the articular cartilage. In this study, MIA-induced OA knee model was used in …
A review of photobiomodulation therapy in bone repair.
PMID: Injury. 2019 Nov ;50(11):1853-1867. Epub 2019 Sep 21. PMID: 31585673 Abstract Title: Photobiomodulation therapy (PBMT) in bone repair: A systematic review. Abstract: BACKGROUND: Photobiomodulation therapy (PBMT) using low-level laser influences the release of several growth factors involved in the formation of epithelial cells, fibroblasts, collagen and vascular proliferation, besides accelerating the synthesis of bone …
Continue reading “A review of photobiomodulation therapy in bone repair.”
Health Time 