Category Archives: Uncategorized

PMID:  Lung Cancer. 2019 Sep ;135:10-15. Epub 2019 Jul 4. PMID: 31446980 Abstract Title:  Residential radon, genetic polymorphisms in DNA damage and repair-related. Abstract:  OBJECTIVES: To analyze the relationship of GSTT1, GSTM1, XRCC1 (rs25487), ERCC1 (rs11615, rs3212986), ERCC2 (rs13181), XRCC3 (rs861539), OGG1 (rs1052133), and Alpha-1-Antitrypsin mutations (AAT) with the risk of lung cancer in never-smokers, …

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PMID:  Neuroreport. 2019 Oct 30. Epub 2019 Oct 30. PMID: 31688419 Abstract Title:  Berberine alleviates rotenone-induced cytotoxicity by antioxidation and activation of PI3K/Akt signaling pathway in SH-SY5Y cells. Abstract:  Berberine, an isoquinoline alkaloid isolated from traditional Chinese medicine, has been widely studied for its efficacy in the treatment of neurodegenerative diseases. However, berberine-mediated neuroprotection in …

Continue reading “Berberine alleviates rotenone-induced cytotoxicity by antioxidation and activation of PI3K/Akt signaling pathway in SH-SY5Y cells.”

PMID:  J Pak Med Assoc. 2019 Aug ;69(Suppl 3)(8):S88-S92. PMID: 31603885 Abstract Title:  Berberine attenuates olanzapine induced-metabolic syndrome. Abstract:  Objective: To elucidate the protective effect of berberine on olanzapine induced-metabolic syndrome.Methods: This prospective experimental study involved thirty Sprague-Dawley male rats which were divided into three groups. Group A (n=10): Rats treated with distilled water, Group …

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PMID:  Psychopharmacology (Berl). 2019 Nov 29. Epub 2019 Nov 29. PMID: 31784805 Abstract Title:  Embedding existential psychology within psychedelic science: reduced death anxiety as a mediator of the therapeutic effects of psychedelics. Abstract:  Psychedelic therapies can engender enduring improvements in psychological well-being. However, relatively little is known about the psychological mechanisms through which the salutary …

Continue reading “Embedding existential psychology within psychedelic science: reduced death anxiety as a mediator of the therapeutic effects of psychedelics.”

PMID:  Lipids. 2019 Nov 6. Epub 2019 Nov 6. PMID: 31691998 Abstract Title:  Berberine Inhibits Adipogenesis in Porcine Adipocytes via AMP-Activated Protein Kinase-Dependent and -Independent Mechanisms. Abstract:  Excessive adipogenesis in adipocytes results in obesity. Berberine, a natural isoquinoline alkaloid, has antiobesity properties. However, the underlying molecular mechanisms have remained unclear up to now. In this …

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PMID:  Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2019 Jul 28 ;35(4):359-362. PMID: 31701723 Abstract Title:  [Effects of berberine on learning and memory ability in vascular cognitive impairment rats]. Abstract:  OBJECTIVE: To investigate the effects of berberine on learning and memory ability in vascular cognitive impairment rats.METHODS: Sixty-eight Wistar rats were randomly divided into …

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PMID:  Cancer Manag Res. 2019 ;11:9005-9015. Epub 2019 Oct 21. PMID: 31695492 Abstract Title:  Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor. Abstract:  Background: Berberine (BBR) from the widely used Chinese herbal medicine Huanglian has an array of pharmacological and biochemical properties, including anti-neoplastic activity. However, the specific mechanisms …

Continue reading “Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor.”

PMID:  Br J Pharmacol. 2019 Nov 16. Epub 2019 Nov 16. PMID: 31734944 Abstract Title:  Berberine protects against diabetic kidney disease via promoting PGC-1α-regulated mitochondrial energy homeostasis. Abstract:  BACKGROUND AND PURPOSE: Lipid metabolism disorder and disturbed mitochondrial bioenergetics play pivotal roles in the occurrence and development of diabetic kidney disease (DKD). Berberine (BBR) is a …

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PMID:  Anticancer Drugs. 2019 Nov 15. Epub 2019 Nov 15. PMID: 31743135 Abstract Title:  Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78. Abstract:  OBJECTIVE: Human colorectal cancer (CRC), a highly malignant and metastatic carcinoma, is resistant to many present anticancer therapies. The inhibition of tumor survival and growth through receptor …

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PMID:  BMC Complement Altern Med. 2019 Nov 19 ;19(1):314. Epub 2019 Nov 19. PMID: 31744490 Abstract Title:  Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88. Abstract:  BACKGROUNDS: Inflammation is recognized as the key pathological mechanism of type 2 diabetes. The hypoglyceamic effects of berberine (BBR) …

Continue reading “Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88.”