Berberine could inhibit renal inflammatory responses and contribute to amelioration of renal injury during systemic inflammation.

PMID:  Mol Med Rep. 2019 Nov 19. Epub 2019 Nov 19. PMID: 31746359 Abstract Title:  Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway. Abstract:  The major role of inner medullary collecting duct (IMCD) cells is to maintain water and sodium homeostasis. In addition to the major …

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.

PMID:  Aging Cell. 2019 Nov 26:e13060. Epub 2019 Nov 26. PMID: 31773901 Abstract Title:  Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression. Abstract:  Although aging and senescence have been extensively studied in the past few decades, however, there is lack of clinical treatment available for anti-aging. …

Berberine decreases insulin resistance in a polycystic ovarian syndrome model.

PMID:  Regul Toxicol Pharmacol. 2019 Nov 25:104544. Epub 2019 Nov 25. PMID: 31778716 Abstract Title:  Berberine decreases insulin resistance in a PCOS rats by improving GLUT4: Dual regulation of the PI3K/AKT and MAPK pathways. Abstract:  Berberine has been found to exhibit an array of pharmacological activities relating to the lowering of blood glucose and the …

Berberine inhibits proliferative ability of breast cancer cells by reducing metadherin.

PMID:  Med Sci Monit. 2019 Nov 28 ;25:9058-9066. Epub 2019 Nov 28. PMID: 31779025 Abstract Title:  Berberine Inhibits Proliferative Ability of Breast Cancer Cells by Reducing Metadherin. Abstract:  BACKGROUND Breast cancer is a common malignant tumor worldwide. Despite the huge advances in modern medicine, many patients still face a high risk of recrudescent and metastatic …

Berberine possesses potential lipid-regulating, antiarthritis, and synovial hyperplasia inhibition activities against rheumatoid arthritis.

PMID:  Evid Based Complement Alternat Med. 2019 ;2019:2580207. Epub 2019 Nov 3. PMID: 31781264 Abstract Title:  Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA. Abstract:  Objective: This study aimed to investigate whether berberine exerted anti-inflammatory and antiproliferative effects on the fibroblast-like synoviocytes of rheumatoid …

Wogonin acts as an ovary cancer cell proliferation inhibiting agent through activation of apoptosis.

PMID:  Med Sci Monit. 2019 Nov 10 ;25:8465-8471. Epub 2019 Nov 10. PMID: 31707402 Abstract Title:  Anti-Proliferative Effect of Wogonin on Ovary Cancer Cells Involves Activation of Apoptosis and Cell Cycle Arrest. Abstract:  BACKGROUND The present study was designed to investigate the effect of wogonin on Caov-3 and A2780 ovary cancer cell proliferation and the …

Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction.

PMID:  Colloids Surf B Biointerfaces. 2019 Nov 10:110635. Epub 2019 Nov 10. PMID: 31744760 Abstract Title:  Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation. Abstract:  Wogonin, one of the main active ingredients of Scutellaria radix, is a kind of flavonoid compound. In the present study, …

Wogonin ameliorate complete Freund’s adjuvant induced rheumatoid arthritis.

PMID:  Biofactors. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31721330 Abstract Title:  Wogonin ameliorate complete Freund's adjuvant induced rheumatoid arthritis via targeting NF-κB/MAPK signaling pathway. Abstract:  Rheumatoid arthritis (RA) is a chronic and accelerated autoimmune illness with proliferative and damaging synovitis, resulting in joint death and cartilage and bone erosion. This study focused on …

Bitter melon has protective anti-inflammatory effects on TNBS-induced colitis.

PMID:  J Med Food. 2019 Nov 8. Epub 2019 Nov 8. PMID: 31702423 Abstract Title:  Anti-Inflammatory Effect of CrudeExtract on 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis Model in Rat and the Bioaccessibility of its Carotenoid Content. Abstract:  known as bitter melon (BM), is a plant that belongs to the family Cucurbitaceae. Aims of this study are to …

Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.

n/a PMID:  Food Sci Nutr. 2019 Nov ;7(11):3443-3451. Epub 2019 Sep 10. PMID: 31762997 Abstract Title:  Piperine as a neuroprotective functional component in rats with cerebral ischemic injury. Abstract:  Long pepper (L.) and black pepper (L.) plants are commonly used as spices around the world and have also been postulated to have medicinal effects. Piperine, …

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