PMID: Biotech Histochem. 2019 Nov 5:1-8. Epub 2019 Nov 5. PMID: 31687851 Abstract Title: The protective effects of thymoquinone on lung damage caused by cigarette smoke. Abstract: Chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation that usually is caused by exposure to noxious particles or gases. Thymoquinone (TQ) prevents the production of inflammatory …
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PMID: Inflammation. 2019 Nov 9. Epub 2019 Nov 9. PMID: 31707574 Abstract Title: Thymoquinone Inhibits Neurogenic Inflammation Underlying Migraine Through Modulation of Calcitonin Gene-Related Peptide Release and Stabilization of Meningeal Mast Cells in Glyceryltrinitrate-Induced Migraine Model in Rats. Abstract: Two main contributors of sterile neurogenic inflammation underlying migraine pain, calcitonin gene-related peptide (CGRP), and meningeal …
PMID: Biofactors. 2019 Nov 23. Epub 2019 Nov 23. PMID: 31758843 Abstract Title: Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid-induced hyperuricemia rats. Abstract: BACKGROUND: Recent studies indicate hyperuricemia as an aggravating factor for kidney diseases progression. Basic research for novel agents to reduce hyperuricemia and kidney abnormalities will …
PMID: BMC Complement Altern Med. 2019 Nov 27 ;19(1):334. Epub 2019 Nov 27. PMID: 31771651 Abstract Title: Thymoquinone-loaded lipid vesicles: a promising nanomedicine for psoriasis. Abstract: BACKGROUND: Psoriasis, a recurrent, chronic inflammatory disorder of skin, is a common problem in middle age and elderly people. Thymoquinone (TQ), a lipid soluble benzoquinone is the major active …
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PMID: J Complement Integr Med. 2019 Oct 26. Epub 2019 Oct 26. PMID: 31675349 Abstract Title: The impact of Crocus sativus stigma against methotrexate-induced liver toxicity in rats. Abstract: Background The adverse effects of methotrexate (MTX) mainly hepatotoxicity restrict its clinical use. This study was designed to investigate the protective effects of saffron (Crocus sativus) …
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PMID: Clin Nutr ESPEN. 2019 Dec ;34:130-136. Epub 2019 Aug 16. PMID: 31677703 Abstract Title: Effect of saffron (Crocus sativus L.) on lipid profile, glycemic indices and antioxidant status among overweight/obese prediabetic individuals: A double-blinded, randomized controlled trial. Abstract: OBJECTIVE: To investigate the effects of saffron (Crocus sativus L.) on lipid profile, glycemic and antioxidant …
PMID: Metab Brain Dis. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31728890 Abstract Title: Neuroprotective effect of Crocus sativus against cerebral ischemia in rats. Abstract: The present study aimed to investigate the role of vascular endothelial growth factor (VEGF) in the neuroprotective effect of Crocus sativus (saffron) against cerebral ischemia/reperfusion injury (I/R) in rats. …
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PMID: Avicenna J Phytomed. 2019 Nov-Dec;9(6):505-516. PMID: 31763210 Abstract Title: Evaluation of the effectiveness of crocin isolated from saffron in treatment of burning mouth syndrome: A randomized controlled trial. Abstract: Objective: Burning mouth syndrome (BMS) is a debilitating disorder with few limited treatment modalities. Because of the proven association between BMS symptoms, and depression and …
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PMID: Phytother Res. 2019 Nov 25. Epub 2019 Nov 25. PMID: 31769107 Abstract Title: Crocin, an active constituent of Crocus sativus ameliorates cerulein induced pancreatic inflammation and oxidative stress. Abstract: Acute pancreatitis (AP) is a disorder of the pancreas marked by profound inflammation and oxidative stress. Phytoconstituents presents an important toolbox of preventive strategies to …
PMID: Food Sci Nutr. 2019 Nov ;7(11):3403-3413. Epub 2019 Sep 18. PMID: 31762993 Abstract Title: Effects of Astragaloside IV on treatment of breast cancer cells execute possibly through regulation of Nrf2 via PI3K/AKT/mTOR signaling pathway. Abstract: Traditional Chinese medicine (TCM) has from ancient times been applied in China for the treatment of breast cancer with …
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