PMID: Mol Med Rep. 2019 Aug ;20(2):1761-1771. Epub 2019 Jun 20. PMID: 31257541 Abstract Title: Sulforaphane has a therapeutic effect in an atopic dermatitis murine model and activates the Nrf2/HO‑1 axis. Abstract: Atopic dermatitis (AD), a chronic inflammatory skin disease, is characterized by intense itching and recurrent eczematous lesions. Sulforaphane is known to attenuate oxidative …
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Effect of sulforaphane and 5-Aza-2′-deoxycytidine on melanoma cell growth.
PMID: Medicines (Basel). 2019 Jun 27 ;6(3). Epub 2019 Jun 27. PMID: 31252639 Abstract Title: Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth. Abstract: UV exposure-induced oxidative stress is implicated as a driving mechanism for melanoma. Increased oxidative stress results in DNA damage and epigenetic dysregulation. Accordingly, we explored whether a low dose of …
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Sulforaphane reduces the apoptosis of neurons in brain trauma-induced diffuse axonal injury.
PMID: J Cell Biochem. 2019 Jun 24. Epub 2019 Jun 24. PMID: 31232487 Abstract Title: Sulforaphane administration alleviates diffuse axonal injury (DAI) via regulation signaling pathway of NRF2 and HO-1. Abstract: BACKGROUND: Nuclear factor erythroid 2-related factor 2 (Nrf2) can alleviate diffuse axonal injury (DAI)-induced apoptosis by regulating expression of heme oxygenase-1 (HO-1), while sulforaphane …
Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma.
PMID: Eur J Pharmacol. 2019 Jul 15 ;855:276-284. Epub 2019 May 14. PMID: 31100413 Abstract Title: Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways. Abstract: Sulforaphane has received considerable attention in recent years due to its antioxidant …
Maternal exposure to bisphenol A during pregnancy interferes ovaries development of F1 female mice.
PMID: Theriogenology. 2019 Sep 27 ;142:138-148. Epub 2019 Sep 27. PMID: 31593881 Abstract Title: Maternal exposure to bisphenol A during pregnancy interferes ovaries development of F1 female mice. Abstract: This study was conducted to investigate the effects of maternal exposure bisphenol A (BPA) on ovaries development of F1 female mice. The BPA exposure model of …
Anti-inflammatory and anti-apoptosis activity of taraxasterol in ulcerative colitis in vitro and in vivo.
PMID: Exp Ther Med. 2019 Sep ;18(3):1745-1751. Epub 2019 Jul 5. PMID: 31410133 Abstract Title: Anti-inflammatory and anti-apoptosis activity of taraxasterol in ulcerative colitisand. Abstract: Ulcerative colitis is closely associated with colorectal cancer, the long-standing chronic inflammation being the key etiology of ulcerative colitis. The aim of the present study was to identify the anti-inflammatory …
Bisphenol A aggravates renal ischemia-reperfusion injury by disrupting mitochondrial homeostasis and N-acetylcysteine mitigates the injurious outcomes.
PMID: IUBMB Life. 2019 Oct 6. Epub 2019 Oct 6. PMID: 31587481 Abstract Title: Bisphenol A aggravates renal ischemia-reperfusion injury by disrupting mitochondrial homeostasis and N-acetylcysteine mitigates the injurious outcomes. Abstract: Exposure to bisphenol A (BPA), a chemical generally used in consumer products, becomes a global public health concern, as humans are increasingly exposed through …
Bisphenol A triggers axonal injury and myelin degeneration with concomitant neurobehavioral toxicity.
PMID: Toxicology. 2019 Sep 28:152299. Epub 2019 Sep 28. PMID: 31574244 Abstract Title: Bisphenol A triggers axonal injury and myelin degeneration with concomitant neurobehavioral toxicity in C57BL/6J male mice. Abstract: Bisphenol A (BPA) is a ubiquitously distributed endocrine disrupting chemical (EDC). Its exposure in humans has been of concern due to its increased application in …
Electroacupuncture can effectively treat dry eye syndrome by improving the symptoms, increasing tear secretion and extending tear film break-up time.
PMID: Curr Eye Res. 2019 Oct 4:1-9. Epub 2019 Oct 4. PMID: 31557061 Abstract Title: A Mechanism Study of Electroacupuncture for Dry Eye Syndrome by Targeting Conjunctival Cytokine Expressions. Abstract: : To discuss the immunological mechanism in electroacupuncture (EA) treatment of dry eye syndrome (DES) by targeting the changes in conjunctival cytokine expression profile.: Eligible …
Bacopasides I and II act in synergy to inhibit the growth, migration and invasion of breast cancer cell lines.
PMID: Molecules. 2019 Sep 30 ;24(19). Epub 2019 Sep 30. PMID: 31574930 Abstract Title: Bacopasides I and II Act in Synergy to Inhibit the Growth, Migration and Invasion of Breast Cancer Cell Lines. Abstract: Bacopaside (bac) I and II are triterpene saponins purified from the medicinal herb. Previously, we showed that bac II reduced endothelial …
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