PMID: Front Microbiol. 2019 ;10:2489. Epub 2019 Nov 5. PMID: 31749783 Abstract Title: Antibacterial Effect and Mode of Action of Flavonoids From Licorice Against Methicillin-Resistant. Abstract: is a bacterial pathogen that causes food poisoning, various infections, and sepsis. Effective strategies and new drugs are needed to controlassociated infections due to the emergence and rapid dissemination …
Author Archives: Taylor Mercado
Licochalcone A has antitumor activities against human osteosarcoma cells.
PMID: Cells. 2019 Nov 14 ;8(11). Epub 2019 Nov 14. PMID: 31739642 Abstract Title: Licochalcone A-Induced Apoptosis Through the Activation of p38MAPK Pathway Mediated Mitochondrial Pathways of Apoptosis in Human Osteosarcoma Cells In Vitro and In Vivo. Abstract: BACKGROUND: Licochalcone A (LicA) is isolated from the roots ofand possesses antitumor and anti-invasive activities against several …
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Licochalcone A might be a potential therapeutic candidate for prevention and treatment of melanoma.
PMID: Phytother Res. 2019 Dec 2. Epub 2019 Dec 2. PMID: 31793097 Abstract Title: Licochalcone A restrains microphthalmia-associated transcription factor expression and growth by activating autophagy in melanoma cells via miR-142-3p/Rheb/mTOR pathway. Abstract: Licochalcone A (LCA) was found to possess anticancer effects. This study aimed to investigate the anticancer effects and mechanisms of LCA in …
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells.
PMID: Bioorg Med Chem Lett. 2020 Jan 15 ;30(2):126825. Epub 2019 Nov 30. PMID: 31836442 Abstract Title: Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor. Abstract: IDH1 mutations are closely related to the development and progression of various human cancers, such as glioblastoma, sarcoma, and acute myeloid …
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Whole-fat yogurt products or cheese in place of milk, regardless of fat content, was associated with a lower risk of development of myocardial infarction.
PMID: J Nutr. 2020 Jan 9. Epub 2020 Jan 9. PMID: 31919508 Abstract Title: Substitution of Milk with Whole-Fat Yogurt Products or Cheese Is Associated with a Lower Risk of Myocardial Infarction: The Danish Diet, Cancer and Health cohort. Abstract: BACKGROUND: Food-based dietary guidelines recommend replacement of whole-fat dairy products with low-fat variants based on …
Pterostilbene prevents early diabetic retinopathy alterations.
PMID: Nutrients. 2019 Dec 27 ;12(1). Epub 2019 Dec 27. PMID: 31892189 Abstract Title: Pterostilbene Prevents Early Diabetic Retinopathy Alterations in a Rabbit Experimental Model. Abstract: Oxidative stress generated by diabetes plays a key role in the development of diabetic retinopathy (DR), a common diabetic complication. DR remains asymptomatic until it reaches advanced stages, which …
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Pterostilbene enhances endurance capacity via promoting skeletal muscle adaptations to exercise training.
PMID: Molecules. 2020 Jan 2 ;25(1). Epub 2020 Jan 2. PMID: 31906449 Abstract Title: Pterostilbene Enhances Endurance Capacity via Promoting Skeletal Muscle Adaptations to Exercise Training in Rats. Abstract: It has been demonstrated that skeletal muscle adaptions, including muscle fibers transition, angiogenesis, and mitochondrial biogenesis are involved in the regular exercise-induced improvement of endurance capacity …
Licochalcone A may serve as a potential therapeutic agent against osteosarcoma.
PMID: Molecules. 2019 Jul 2 ;24(13). Epub 2019 Jul 2. PMID: 31269698 Abstract Title: Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation. Abstract: Licochalcone A, a flavonoid extracted from licorice root, has been shown to exhibit broad anti-inflammatory, anti-bacterial, anticancer, and antioxidative bioactivity. In this study, we investigated the antitumor …
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Dietary apple polyphenols promote fat browning in high-fat diet-induced obese mice.
PMID: J Sci Food Agric. 2020 Jan 9. Epub 2020 Jan 9. PMID: 31916584 Abstract Title: Dietary apple polyphenols promote fat browning in high-fat diet-induced obese mice through activation of AMP-activated protein kinase (AMPK)α. Abstract: BACKGROUND: Promoting brown and beige adipogenesis contributes to adaptive thermogenesis, which provides a defense against obesity and related disorders. Apple …
The seed of Litchi chinensis fraction ameliorates hippocampal neuronal injury in an Aβ25-35-induced Alzheimer’s disease.
PMID: Pharm Biol. 2020 Dec ;58(1):35-43. PMID: 31881157 Abstract Title: The seed offraction ameliorates hippocampal neuronal injury in an Aβ-induced Alzheimer's disease rat model via the AKT/GSK-3β pathway. Abstract: The seed ofSonn., a famous traditional Chinese medicine, was recently reported to enhance cognitive function by inhibiting neuronal apoptosis in rats.We determined whether the seed offraction …
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