PMID: J Nutr Biochem. 2019 Aug 31 ;74:108228. Epub 2019 Aug 31. PMID: 31678747 Abstract Title: Kaempferol stimulates WNT/β-catenin signaling pathway to induce differentiation of osteoblasts. Abstract: Flavonoids, a group of natural compounds found in a variety of vegetables and herbal medicines, have been intensively reported on stimulating bone mineral density and bone formation. Among …
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Kaempferol protects retinal ganglion ceils from high-glucose-induced injury by regulating vasohibin-1.
PMID: Neurosci Lett. 2019 Nov 16:134633. Epub 2019 Nov 16. PMID: 31743752 Abstract Title: Kaempferol protects retinal ganglion ceils from high-glucose-induced injury by regulating vasohibin-1. Abstract: Kaempferol is a medicinal flavonol derived from the roots of Kaempferia galanga L. Kaempferol can affect cell survival, apoptosis, and anti-oxidation, though its role and underlying mechanism in retinal …
Dietary berries, insulin resistance and type 2 diabetes: an overview of human feeding trials.
PMID: Food Funct. 2019 Oct 16 ;10(10):6227-6243. PMID: 31591634 Abstract Title: Dietary berries, insulin resistance and type 2 diabetes: an overview of human feeding trials. Abstract: Dietary berries are a rich source of several nutrients and phytochemicals and in recent years, accumulating evidence suggests they can reduce risks of several chronic diseases, including type 2 …
Protective effects of Fragaria ananassa methanolic extract in a rat model of cadmium chloride-induced neurotoxicity.
PMID: Biosci Rep. 2018 12 21 ;38(6). Epub 2018 Nov 15. PMID: 30291211 Abstract Title: Protective effects ofmethanolic extract in a rat model of cadmium chloride-induced neurotoxicity. Abstract: Cadmium (Cd) is a common environmental toxicant that has harmful effects on plants, animals, and humans. The present study evaluated the protective effects ofmethanolic extract (SME) on …
E-Cigarette Ban and Vaping CBD
In September, The Trump Administration announced a proposed ban on flavored e-cigarettes. Alex Azar, the Health and Human Services Secretary said the FDA will enact the policy soon. The proposed ban so far does not mention CBD or vitamin vape cartridges, leaving many questions on the fate of non-nicotine vape products. The ban is a …
Artesunate and sorafenib: Combinatorial inhibition of liver cancer cell growth.
PMID: Oncol Lett. 2019 Nov ;18(5):4735-4743. Epub 2019 Sep 5. PMID: 31611983 Abstract Title: Artesunate and sorafenib: Combinatorial inhibition of liver cancer cell growth. Abstract: An antimalarial medication, artesunate (Art), has exhibited promising anticancer effects with excellent tolerability in various types of cancer, suggesting that it has the potential to be used in combination with …
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Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells.
PMID: Cell Death Dis. 2019 Nov 13 ;10(11):862. Epub 2019 Nov 13. PMID: 31723124 Abstract Title: Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6. Abstract: Retinoblastoma (RB) is the most common primary intraocular malignancy in children. Intravitreal chemotherapy achieves favorable clinical outcomes in controlling RB vitreous seeds, which are a …
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Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.
PMID: J Cell Mol Med. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31746143 Abstract Title: Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence. Abstract: Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have demonstrated that artemisinin (ARS) compounds …
Continue reading “Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.”
Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis.
PMID: Food Funct. 2018 Dec 13 ;9(12):6218-6226. PMID: 30382270 Abstract Title: Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis. Abstract: OBJECTIVE: Knee osteoarthritis (OA) is increasingly prevalent in obese people, who often have high cardio-metabolic risk factors. Among the few available non-surgical approaches, nutraceuticals have gained …
Following H1N1 influenza vaccination, H1N1 antibodies were associated with young age-at-onset narcolepsy.
PMID: J Autoimmun. 2014 May ;50:99-106. Epub 2014 Jan 29. PMID: 24485154 Abstract Title: A/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010. Abstract: Narcolepsy is a lifelong sleep disorder related to hypocretin deficiency resulting from a specific loss of hypocretin-producing neurons in the lateral …
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