Measles titers decline at an average rate of 9.7% per year.

PMID:  Vaccine. 2018 02 1 ;36(6):818-826. Epub 2018 Jan 6. PMID: 29317117 Abstract Title:  Measles, mumps, and rubella antibody patterns of persistence and rate of decline following the second dose of the MMR vaccine. Abstract:  BACKGROUND: Antibodies to measles, mumps, and rubella decline 3% per year on average, and have a high degree of individual …

Decline of aspirin use is associated with a decreased incidence of Reye’s syndrome.

PMID:  Pediatrics. 1987 Jun ;79(6):858-63. PMID: 3588140 Abstract Title:  National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985. Abstract:  The number of cases of Reye syndrome reported annually to the Centers for Disease Control declined markedly between 1980 and 1985. In this article, we present pharmaceutical marketing research data that …

Endotoxemia with vaccination resulted in significanyt behavioral alterations in concomitance with an increase in biomarkers for oxidative stress and inflammation. This was not attentuated by paracetamol.

PMID:  Inflammopharmacology. 2018 Aug ;26(4):951-961. Epub 2018 Jan 11. PMID: 29327281 Abstract Title:  Effect of early natal supplementation of paracetamol on attenuation of exotoxin/endotoxin induced pyrexia and precipitation of autistic like features in albino rats. Abstract:  The present study was aimed to test the hypothesis that paracetamol (PCM) can precipitate autistic like features when used …

Fortification of food with vitamin A or zinc, not immunization, was the most cost effective intervention to promote children’s health.

PMID:  BMJ. 2005 Nov 19 ;331(7526):1177. Epub 2005 Nov 10. PMID: 16282378 Abstract Title:  Cost effectiveness analysis of strategies for child health in developing countries. Abstract:  OBJECTIVE: To determine the costs and effectiveness of selected child health interventions-namely, case management of pneumonia, oral rehydration therapy, supplementation or fortification of staple foods with vitamin A or …

Decline in mortality preceded vaccination.

PMID:  JAMA. 1999 Jan 6 ;281(1):61-6. PMID: 9892452 Abstract Title:  Trends in infectious disease mortality in the United States during the 20th century. Abstract:  CONTEXT: Recent increases in infectious disease mortality and concern about emerging infections warrant an examination of longer-term trends.OBJECTIVE: To describe trends in infectious disease mortality in the United States during the …

All children diagnosed with autism following MMR vaccination presented with intestinal abnormalities, according to this study.

PMID:  Lancet. 1998 02 28 ;351(9103):637-41. PMID: 9500320 Abstract Title:  Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Abstract:  BACKGROUND: We investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder.METHODS: 12 children (mean age 6 years [range 3-10], 11 boys) were referred to a paediatric gastroenterology unit with a …

An increased number of autoimmune disorders suggests that in some families with autism, immune dysfunction could interact with various environmental factors to play a role in autism pathogenesis.

PMID:  J Child Neurol. 1999 Jun ;14(6):388-94. PMID: 10385847 Abstract Title:  Familial clustering of autoimmune disorders and evaluation of medical risk factors in autism. Abstract:  Autism is an age-dependent neurologic disorder that is often associated with autoimmune disorders in the patients' relatives. To evaluate the frequency of autoimmune disorders, as well as various prenatal and …

Parental autoimmunity is associated with autism spectrum disorders in offspring.

PMID:  Epidemiology. 2010 Nov ;21(6):805-8. PMID: 20798635 Abstract Title:  Parental autoimmune diseases associated with autism spectrum disorders in offspring. Abstract:  BACKGROUND: Autism spectrum disorders are often idiopathic. Studies have suggested associations between immune response and these disorders. We explored associations between parental autoimmune disorders and children's diagnosis of autism by linking Swedish registries.METHODS: Data for …

There is an overall increased risk of autism in children with a family history of autoimmune diseases.

PMID:  Neurosci Biobehav Rev. 2015 Aug ;55:322-32. Epub 2015 May 15. PMID: 25981892 Abstract Title:  Family history of autoimmune diseases is associated with an increased risk of autism in children: A systematic review and meta-analysis. Abstract:  BACKGROUND: We conducted a systematic review and meta-analysis to summarize the current evidence on the relationship between family history …

Neuroinflammatory mechanisms may contribute to the pathogenesis of different intellectual disabilities and autism-associated disorders.

PMID:  CNS Neurol Disord Drug Targets. 2016 ;15(4):448-63. PMID: 26996174 Abstract Title:  Neuro-Inflammatory Mechanisms in Developmental Disorders Associated with Intellectual Disability and Autism Spectrum Disorder: A Neuro- Immune Perspective. Abstract:  Intellectual disability (ID) and autism are present in several neurodevelopmental disorders and are often associated in genetic syndromes, such as Fragile X and Rett syndromes. …

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