Epidemiological data supports an increased incidence of narcolepsy following the H1N1 vaccination.

PMID:  Lancet Neurol. 2014 Jun ;13(6):600-13. PMID: 24849861 Abstract Title:  Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination. Abstract:  Narcolepsy is a sleep disorder characterised by loss of hypothalamic hypocretin (orexin) neurons. The prevalence of narcolepsy is about 30 per 100 000 people, and typical age at onset is 12-16 years. Narcolepsy …

In this study, incidence of narcolepsy was 25 times higher after vaccination compared to the time period before.

PMID:  Neurology. 2013 Apr 2 ;80(14):1315-21. Epub 2013 Mar 13. PMID: 23486871 Abstract Title:  Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination. Abstract:  OBJECTIVES: To assess the incidence of narcolepsy between January 2000 and December 2010 in children in western Sweden and its relationship to the Pandemrix vaccination, and to compare …

Healthcare worker influenza vaccination does not have a significant effect of hospital-originated influenza.

PMID:  Infect Control Hosp Epidemiol. 2016 07 ;37(7):840-4. Epub 2016 Apr 21. PMID: 27098758 Abstract Title:  Potential Ceiling Effect of Healthcare Worker Influenza Vaccination on the Incidence of Nosocomial Influenza Infection. Abstract:  OBJECTIVE To evaluate the effect of healthcare worker (HCW) influenza vaccination on the incidence of nosocomial influenza DESIGN Retrospective cross-sectional study SETTING A …

Guillain-Barre syndrome can occur after either monovalent or trivalent influenza vaccines.

PMID:  J Korean Med Sci. 2017 Jul ;32(7):1154-1159. PMID: 28581273 Abstract Title:  Clinical Features of Post-Vaccination Guillain-Barré Syndrome (GBS) in Korea. Abstract:  Guillain-Barré syndrome (GBS) is the most common immune-mediated polyradiculoneuropathy and it is also the most commonly reported severe adverse event following immunization in adults. To evaluate the results of clinical and laboratory features …

The 2014-2015 influenza vaccine was an antigenic mismatch, however, even in the context of antigenic mismatch, there is a generally limited antibody response following the vaccination.

PMID:  Clin Infect Dis. 2017 Oct 30 ;65(10):1644-1651. PMID: 29020179 Abstract Title:  The Household Influenza Vaccine Effectiveness Study: Lack of Antibody Response and Protection Following Receipt of 2014-2015 Influenza Vaccine. Abstract:  Background: Antigenically drifted A(H3N2) viruses circulated extensively during the 2014-2015 influenza season. Vaccine effectiveness (VE) was low and not significant among outpatients but in …

The evidence for a lower risk of influenza and influenza-like illness in the elderly with vaccination is limited by biases in the design or conduct of the studies.

PMID:  Cochrane Database Syst Rev. 2018 02 1 ;2:CD004876. Epub 2018 Feb 1. PMID: 29388197 Abstract Title:  Vaccines for preventing influenza in the elderly. Abstract:  BACKGROUND: The consequences of influenza in the elderly (those age 65 years or older) are complications, hospitalisations, and death. The primary goal of influenza vaccination in the elderly is to …

Healthy adults who receive the inactivated influenza vaccine only have a 1% lower risk of experiencing influenza over a single influenza season and a 3.4% lower risk of experiencing influenza-like illness.

PMID:  Cochrane Database Syst Rev. 2018 02 1 ;2:CD001269. Epub 2018 Feb 1. PMID: 29388196 Abstract Title:  Vaccines for preventing influenza in healthy adults. Abstract:  BACKGROUND: The consequences of influenza in adults are mainly time off work. Vaccination of pregnant women is recommended internationally. This is an update of a review published in 2014. Future …

The efficacy of the influenza vaccine in children under two years old has not been well studied for safety or efficacy.

PMID:  Cochrane Database Syst Rev. 2018 02 1 ;2:CD004879. Epub 2018 Feb 1. PMID: 29388195 Abstract Title:  Vaccines for preventing influenza in healthy children. Abstract:  BACKGROUND: The consequences of influenza in children and adults are mainly absenteeism from school and work. However, the risk of complications is greatest in children and people over 65 years …

Resurgence of the whopping cough in the UK is likely attributed to vaccine failure.

PMID:  Vaccine. 2013 Dec 2 ;31(49):5903-8. Epub 2013 Oct 16. PMID: 24139837 Abstract Title:  Can vaccine legacy explain the British pertussis resurgence? Abstract:  Pertussis incidence has been rising in some countries, including the UK, despite sustained high vaccine coverage. We questioned whether it is possible to explain the resurgence without recourse to complex hypotheses about …

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