PMID: PLoS One. 2019 ;14(10):e0223070. Epub 2019 Oct 17. PMID: 31622373 Abstract Title: Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation. Abstract: The present study evaluates the effect of flaxseed oil (FXO) supplementation on adipose tissue macrophages (ATM's), E and D …
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Beneficial effects of flaxseed and its components on mammary gland MiRNome.
PMID: Nutrients. 2019 Nov 4 ;11(11). Epub 2019 Nov 4. PMID: 31689992 Abstract Title: Effects of Flaxseed and Its Components on Mammary Gland MiRNome: Identification of Potential Biomarkers to Prevent Breast Cancer Development. Abstract: Breast cancer is the most common cancer among women worldwide. We previously showed that early-life exposure to flaxseed (FS) or its …
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Addition of flaxseed to yogurt can be effective in the management of type 2 diabetes.
PMID: Clin Nutr Res. 2019 Oct ;8(4):284-295. Epub 2019 Oct 2. PMID: 31720254 Abstract Title: The Effect of Flaxseed Enriched Yogurt on the Glycemic Status and Cardiovascular Risk Factors in Patients with Type 2 Diabetes Mellitus: Randomized, Open-labeled, Controlled Study. Abstract: : Flaxseed is one of the rich sources ofα-linolenic acid and lignan. Flaxseed and …
An artificial tear containing flaxseed oil could be useful for treating dry eye disease.
PMID: Ocul Surf. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31734510 Abstract Title: An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial. Abstract: PURPOSE: To evaluate the efficacy and safety of a nano-emulsion artificial tear (OM3) containing carboxymethylcellulose (CMC) and glycerin, flaxseed oil and castor oil, and three …
Flaxseed supplementation may improve some circulating concentrations of specific adhesion molecules and inflammatory cytokines.
PMID: Cytokine. 2019 Nov 15 ;126:154922. Epub 2019 Nov 15. PMID: 31739218 Abstract Title: Effect of flaxseed supplementation on markers of inflammation and endothelial function: A systematic review and meta-analysis. Abstract: OBJECTIVES: The rationale for the current study was to evaluate the efficacy of flaxseed supplementation on important adhesion molecules and inflammatory cytokines in adults.METHODS: …
Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells.
PMID: Oncol Rep. 2019 Nov ;42(5):1904-1914. Epub 2019 Aug 28. PMID: 31485597 Abstract Title: Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells. Abstract: Apoptosis is regarded as a therapeutic target because it is typically disturbed in human cancer. Silymarin from milk thistle (Silybum …
Silymarin monotherapy can be a therapeutic option for the treatment of acne vulgaris.
PMID: Dermatol Ther. 2019 Oct 3:e13095. Epub 2019 Oct 3. PMID: 31579978 Abstract Title: Efficacy and safety of oral silymarin in comparison with oral doxycycline and their combination therapy in the treatment of acne vulgaris. Abstract: Two factors of oxidative stress and inflammatory processes are implicated in pathogenesis of acne vulgaris. Silymarin has antioxidant and …
The results demonstrate that silymarin protects against MPTP-induced changes in autophagy leading to Parkinsonism.
PMID: J Mol Neurosci. 2019 Nov 15. Epub 2019 Nov 15. PMID: 31732923 Abstract Title: Silymarin Protects Against Impaired Autophagy Associated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinsonism. Abstract: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exacerbates mitochondrial impairment andα-synuclein expression leading to Parkinsonism. Impaired mitochondria and over-expressed α-synuclein are degraded and eliminated via macroautophagy and chaperone-mediated autophagy. Owing to multiple properties, silymarin protects …
Hepatoprotective effect of artichoke leaf extracts in comparison with silymarin on acetaminophen-induced hepatotoxicity.
PMID: J Immunoassay Immunochem. 2019 Nov 18:1-13. Epub 2019 Nov 18. PMID: 31739724 Abstract Title: Hepatoprotective effect of artichoke leaf extracts in comparison with silymarin on acetaminophen-induced hepatotoxicity in mice. Abstract: Acetaminophen is a common analgesic-antipyretic agent, which is safe in therapeutic doses but in higher doses can produce hepatic necrosis. The aim of this …
Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease.
PMID: Phytother Res. 2018 Jul ;32(7):1382-1387. Epub 2018 Mar 9. PMID: 29520889 Abstract Title: Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial. Abstract: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide and is potentially treatable, though there are few therapeutic …
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