The Bordatella pertussis virus is evolving through vaccine-driven adaptation.

PMID:  Emerg Infect Dis. 2014 Apr ;20(4):626-33. PMID: 24655754 Abstract Title:  Rapid increase in pertactin-deficient Bordetella pertussis isolates, Australia. Abstract:  Acellular vaccines against Bordetella pertussis were introduced in Australia in 1997. By 2000, these vaccines had replaced whole-cell vaccines. During 2008-2012, a large outbreak of pertussis occurred. During this period, 30% (96/320) of B. pertussis …

Artichoke extract improved the expression of genes involved in anti-ageing mechanisms.

PMID:  Molecules. 2018 Oct 23 ;23(11). Epub 2018 Oct 23. PMID: 30360471 Abstract Title:  Artichoke Polyphenols Produce Skin Anti-Age Effects by Improving Endothelial Cell Integrity and Functionality. Abstract:  Artichoke is a characteristic crop of the Mediterranean area, recognized for its nutritional value and therapeutic properties due to the presence of bioactive components such as polyphenols, …

Varicella vaccine recipients over age 60 shed virus DNA in their saliva up to 4 weeks post-vaccination.

PMID:  J Infect Dis. 2011 Jun 1 ;203(11):1542-5. PMID: 21592982 Abstract Title:  Varicella zoster virus DNA at inoculation sites and in saliva after Zostavax immunization. Abstract:  Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization …

Vaccination can result in demyelination of the central nervous system, with some cases taking up to 5 months to manifest.

PMID:  Autoimmun Rev. 2014 Mar ;13(3):215-24. PMID: 24514081 Abstract Title:  The spectrum of post-vaccination inflammatory CNS demyelinating syndromes. Abstract:  A wide variety of inflammatory diseases temporally associated with the administration of various vaccines, has been reported in the literature. A PubMed search from 1979 to 2013 revealed seventy one (71) documented cases. The most commonly …

These findings suggest that Cynara leaves exert antiobesity and antioxidant liver effects in HFD-induced obese rats.

PMID:  Biomed Res Int. 2019 ;2019:4851279. Epub 2019 May 23. PMID: 31240213 Abstract Title:  LC-MS/MS Analysis and Hepatoprotective Activity of Artichoke (L.) Leaves Extract against High Fat Diet-Induced Obesity in Rats. Abstract:  L. (Artichoke) has been used for the treatment of metabolic disorders. The purpose of the present study was to investigate the hepatoprotective effect …

Peptide cross-reactivity may potentiate autoimmune cross-reactions.

PMID:  Front Biosci (Schol Ed). 2012 Jun 1 ;4:1393-401. Epub 2012 Jun 1. PMID: 22652881 Abstract Title:  Peptide cross-reactivity: the original sin of vaccines. Abstract:  Recent numerous studies have demonstrated that an extensive peptide identity platform characterizes entities spanning the entire evolutionary arc from viruses to humans and establishes an immune cross-reactivity potential among viruses …

There is a signficant increased risk of adverse events following immunization in patients with primary immunodeficiency diseases.

PMID:  Vaccine. 2016 Mar 18 ;34(13):1611-1616. Epub 2016 Feb 2. PMID: 26850760 Abstract Title:  Adverse events following immunization in patients with primary immunodeficiencies. Abstract:  BACKGROUND: Adverse events following immunization (AEFI) requires special consideration in patients with primary immunodeficiency diseases (PID) because they may represent a"red flag"for the initial diagnosis and may cause disease complications. Therefore, …

Maternal exposure to excess aluminum can lead to neurobehavioral deficits in offspring, according to animal studies.

PMID:  Neurotoxicol Teratol. 1995 Jul-Aug;17(4):515-21. PMID: 7565498 Abstract Title:  Reproductive and developmental toxicity of aluminum: a review. Abstract:  It is well known that aluminum is a developmental toxicant when administered parenterally. However, until recently, there was little concern about embryo/fetal consequences of aluminum ingestion because bioavailability was considered low. The importance of the route of …

Aluminum adjuvants may have potentially distinct roles in vaccine-related adverse events.

PMID:  Allergy Asthma Clin Immunol. 2018 ;14:80. Epub 2018 Nov 7. PMID: 30455719 Abstract Title:  Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action. Abstract:  Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are …

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