Polysorbate 80 has depressive effects on the cardiovascular system.

PMID:  Arzneimittelforschung. 1985 ;35(5):804-8. PMID: 4026903 Abstract Title:  Polysorbate 80: a pharmacological study. Abstract:  Polyoxyethylene (20) sorbitan monooleate (polysorbate 80, Tween 80), a surfactant, has been widely used as a solvent for pharmacological experiments. In the present study, polysorbate 80 was found to have toxicity of a low order in both the mice and rats …

Thimerosal injection increases calbindin expression in the brain.

PMID:  J Toxicol Environ Health A. 2016 ;79(12):502-12. PMID: 27294299 Abstract Title:  A brain proteome profile in rats exposed to methylmercury or thimerosal (ethylmercury). Abstract:  Exposure to organomercurials has been associated with harmful effects on the central nervous system (CNS). However, the mechanisms underlying organomercurial-mediated neurotoxic effects need to be elucidated. Exposure to toxic elements …

Thimerosal had a higher affinity for the brain than mercuric chloride following subcutaneous injection in rats.

PMID:  J Biomed Biotechnol. 2012 ;2012:256965. Epub 2012 Jul 26. PMID: 22899883 Abstract Title:  Mercury disposition in suckling rats: comparative assessment following parenteral exposure to thiomersal and mercuric chloride. Abstract:  Due to the facts that thiomersal-containing vaccine is still in use in many developing countries, and all forms of mercury have recognised neurotoxic, nephrotoxic, and …

Mangosteen pericarp could be an adjunctive treatment option for mood and psychotic disorders.

PMID:  Front Psychiatry. 2019 ;10:115. Epub 2019 Mar 13. PMID: 30918489 Abstract Title:  The Therapeutic Potential of Mangosteen Pericarp as an Adjunctive Therapy for Bipolar Disorder and Schizophrenia. Abstract:  New treatments are urgently needed for serious mental illnesses including bipolar disorder and schizophrenia. This review proposes that. (mangosteen) pericarp is a possible adjunctive therapeutic agent …

These findings suggest that blackberry consumption could help prevent or reduce manic episodes.

PMID:  Neurosci Lett. 2020 Jan 1 ;714:134566. Epub 2019 Nov 4. PMID: 31698027 Abstract Title:  Blackberry extract improves behavioral and neurochemical dysfunctions in a ketamine-induced rat model of mania. Abstract:  Bipolar disorder is a chronic mood disorder characterized by episodes of mania and depression. The aim of this study was to investigate the effects of …

Mangosteen vinegar rind could be a dietary aid for the prevention and management of diabetic nephropathy.

PMID:  J Food Sci. 2019 May ;84(5):1208-1215. Epub 2019 Apr 23. PMID: 31012974 Abstract Title:  Mangosteen Vinegar Rind from Garcinia mangostana Prevents High-Fat Diet and Streptozotocin-Induced Type II Diabetes Nephropathy and Apoptosis. Abstract:  Type II diabetes (T2D) nephropathy, a major cause of end-stage kidney disease, progresses and develops from oxidative stress. Natural polyphenols can protect …

Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.

PMID:  Pharm Biol. 2018 Dec ;56(1):455-464. PMID: 31070537 Abstract Title:  Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate. Abstract:  CONTEXT: Garcinia mangostana Linn. (Guttiferae) pericarp is used as a traditional medicine in South Asia to treat inflammatory diseases.OBJECTIVE: This study investigates therapeutic effects of G. mangostana …

Mangosteen flesh supplementation attenuates biochemical and morphological changes in the liver and kidney of high fat diet-induced obesity.

PMID:  BMC Complement Altern Med. 2019 Dec 2 ;19(1):344. Epub 2019 Dec 2. PMID: 31791316 Abstract Title:  Mangosteen (Garcinia mangostana) flesh supplementation attenuates biochemical and morphological changes in the liver and kidney of high fat diet-induced obese rats. Abstract:  BACKGROUND: Mangosteen is a native fruit from Southeast Asia. It is rich in phenolic compounds such …

Attenuating effects of Mangifera indica leaves ethanolic extract against acetamiprid induced reproductive toxicity.

PMID:  Vet Res Forum. 2019 ;10(3):187-192. Epub 2019 Sep 15. PMID: 31737226 Abstract Title:  Attenuating effects ofleaves ethanolic extract against acetamiprid induced reproductive toxicity in male guinea pigs. Abstract:  Acetamiprid (ACP) belonging to the neonicotinoid family used against wide array of pests in agriculture and domestic purposes. In this study, we evaluated the attenuating effects …

Mangiferin may attenuate atherogenesis by promoting cholesterol efflux from macrophages.

PMID:  Aging (Albany NY). 2019 Dec 2 ;11. Epub 2019 Dec 2. PMID: 31790366 Abstract Title:  Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1. Abstract:  Mangiferin has been identified as a potent cardioprotective factor that enhances high-density lipoprotein cholesterol levels in plasma. The aim of this …

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