PMID: J Stroke Cerebrovasc Dis. 2019 Nov 11:104483. Epub 2019 Nov 11. PMID: 31727597 Abstract Title: Gastrodin Attenuates Neuronal Apoptosis and Neurological Deficits after Experimental Intracerebral Hemorrhage. Abstract: OBJECTIVE: Gastrodin, a glucoside of gastrodigenin, inhibits cerebral oxidant stress and apoptosis in multiple central nervous system injury, but its effect in intracerebral hemorrhage (ICH) remains unclear. …
Category Archives: Uncategorized
ginsenosides Rb could significantly improve anaemia and hypercoagulation of blood in cancer.
PMID: Biomed Res Int. 2019 ;2019:5476076. Epub 2019 Aug 18. PMID: 31531357 Abstract Title: Study on the Effect of Ginsenosides Rb on Blood of Tumor Mice. Abstract: Objective: The blood of cancer patients is in a state of hypercoagulability, easily leading to thrombosis. Anemia is also a complication of tumors. Anemia and thrombosis affect the …
MicroRNAs mediate the anti-tumor and protective effects of ginsenosides.
PMID: Nutr Cancer. 2019 Oct 12:1-12. Epub 2019 Oct 12. PMID: 31608663 Abstract Title: MicroRNAs mediate the anti-tumor and protective effects of ginsenosides. Abstract: MicroRNAs (miRs(, as short non-coding RNAs, regulate important biological processes and mainly are associated with regulation of gene expression. The miRs are beneficial targets for diagnosis of various disorders, particularly cancer, …
Continue reading “MicroRNAs mediate the anti-tumor and protective effects of ginsenosides.”
Recent advances in ginsenosides as potential therapeutics against breast cancer.
PMID: Curr Top Med Chem. 2019 Oct 17. Epub 2019 Oct 17. PMID: 31648643 Abstract Title: Recent Advances in Ginsenosides as Potential Therapeutics Against Breast Cancer. Abstract: The dried root of ginseng (Panax ginseng C. A. Meyer or Panax quinquefolius L.) is a traditional Chinese medicine widely used to manage cancer symptoms and chemotherapy side …
Continue reading “Recent advances in ginsenosides as potential therapeutics against breast cancer.”
Functional regulation of ginsenosides on myeloid immunosuppressive cells in the tumor microenvironment.
PMID: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419886655. PMID: 31729239 Abstract Title: Functional Regulation of Ginsenosides on Myeloid Immunosuppressive Cells in the Tumor Microenvironment. Abstract: Ginsenosides, the key components isolated from ginseng, have been extensively studied in antitumor treatment. Numerous studies have shown that ginsenosides have direct function in tumor cells through the induction of cancer cell …
Paeoniflorin alleviates H2O2-Induced oxidative injury through down-regulation of microRNA-135a in HT-22 cells.
PMID: Neurochem Res. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31728857 Abstract Title: Paeoniflorin Alleviates HO-Induced Oxidative Injury Through Down-Regulation of MicroRNA-135a in HT-22 Cells. Abstract: Paeoniflorin (PF) has been reported to possess neuroprotective influences on cognitive dysfunction illness. In current research, we attempted to probe into the protective influences of PF against HO-induced …
Encapsulation of crocetin into nanoparticles overcomes drug resistance in human ovarian cisplatin-resistant carcinoma cell line.
PMID: Mol Biol Rep. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31646427 Abstract Title: Encapsulation of crocetin into poly (lactic-co-glycolic acid) nanoparticles overcomes drug resistance in human ovarian cisplatin-resistant carcinoma cell line (A2780-RCIS). Abstract: Nanoparticles and herbal medicines have gained considerable attention in overcoming multidrug resistance through different mechanisms. In this study, the effects …
The association of cigarette smoke exposure with lung cellular toxicity and oxidative stress: the protective role of crocin.
PMID: Inflammation. 2019 Oct 28. Epub 2019 Oct 28. PMID: 31659585 Abstract Title: The Association of Cigarette Smoke Exposure with Lung Cellular Toxicity and Oxidative Stress: the Protective Role of Crocin. Abstract: Cigarette smoke (CS) contains many free radicals and toxic chemicals. Nuclear erythroid-related factor-2 (Nrf2) is a transcriptional regulator of several phase II antioxidant …
Crocin protects cardiomyocytes against lipopolysaccharide-Induced inflammation.
PMID: Pharmacol Rep. 2019 Jul 30 ;71(6):1228-1234. Epub 2019 Jul 30. PMID: 31670059 Abstract Title: Crocin protects cardiomyocytes against LPS-Induced inflammation. Abstract: BACKGROUND: Sepsis causes organ dysfunctions via elevation of oxidative stress and inflammation. Lipopolysaccharide (LPS) is the major surface molecule of most gram-negative bacteria and routinely used as a sepsis model in investigation studies. …
Continue reading “Crocin protects cardiomyocytes against lipopolysaccharide-Induced inflammation.”
Ameliorative effect of crocin on sperm parameters and in vitro fertilization in mice under oxidative stress induced by paraquat.
PMID: Int J Fertil Steril. 2020 Jan ;13(4):307-314. Epub 2019 Nov 11. PMID: 31710192 Abstract Title: Ameliorative Effect of Crocin on Sperm Parameters and In Vitro Fertilization in Mice under Oxidative Stress Induced by Paraquat. Abstract: Background: Paraquat (PQ) is an herbicide that is genotoxic and cytotoxic for male germ cells. In this study, we …
Health Time 