PMID: Food Funct. 2019 Nov 1 ;10(11):7461-7475. Epub 2019 Oct 31. PMID: 31667483 Abstract Title: The effect of crocetin supplementation on markers of atherogenic risk in patients with coronary artery disease: a pilot, randomized, double-blind, placebo-controlled clinical trial. Abstract: BACKGROUND AND PURPOSE: Molecular mechanisms of atherogenesis are considered to be emerging therapeutic targets for atherosclerosis …
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This study indicates the beneficial properties of astaxanthin in alleviation of cognitive functions and reducing neurodegeneration.
PMID: Mar Drugs. 2019 Nov 4 ;17(11). Epub 2019 Nov 4. PMID: 31690015 Abstract Title: Effects of Astaxanthin from Shrimp Shell on Oxidative Stress and Behavior in Animal Model of Alzheimer's Disease. Abstract: This study aimed to investigate the effect of astaxanthin (ASX) extracted and ASX powder from shrimp () shells on Wistar rats with …
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
PMID: Mol Med Rep. 2019 Nov ;20(5):4612-4622. Epub 2019 Oct 1. PMID: 31702040 Abstract Title: Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism. Abstract: The aim of the present study was to evaluate the protective effect and mechanism of Astragaloside IV (ASIV) on myocardial injury induced by type 2 diabetes, with …
Astragaloside-IV protects H9C2(2-1) cardiomyocytes from high glucose-induced injury via miR-34a-mediated autophagy pathway.
PMID: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):4172-4181. PMID: 31713440 Abstract Title: Astragaloside-IV protects H9C2(2-1) cardiomyocytes from high glucose-induced injury via miR-34a-mediated autophagy pathway. Abstract: Diabetic cardiomyopathy (DCM) is an important cardiac disorder in patients with diabetes. High glucose (HG) levels lead to inflammation of cardiomyocytes, oxidative stress, and long-term activation of autophagy, resulting in …
Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-β/Smads pathway.
PMID: J Ethnopharmacol. 2019 Nov 15:112404. Epub 2019 Nov 15. PMID: 31739105 Abstract Title: Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-β/Smads pathway. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Cardiac fibrosis is a common characteristic of many cardiac diseases. Our previous results showed that TRPM7 channel played an important role in the fibrosis process. MicroRNA-135a was reported to get …
The experimental results help to further understand the antioxidant effects of astaxanthin.
PMID: J Agric Food Chem. 2019 Nov 11. Epub 2019 Nov 11. PMID: 31709793 Abstract Title: Studies on Protection of Astaxanthin from Oxidative Damage Induced by H2O2 in RAW264.7 Cells Based on 1H NMR Metabolomics. Abstract: Astaxanthin (AST), a fat-soluble and non-vitamin A source of carotenoid which can quench reactive oxygen species and it has …
Astaxanthin given in the post injury period significantly decreases fibrosis.
PMID: J Clin Med. 2019 Nov 11 ;8(11). Epub 2019 Nov 11. PMID: 31718054 Abstract Title: The Effects of Postoperative Astaxanthin Administration on Nasal Mucosa Wound Healing. Abstract: : .BACKGROUND: Wound healing of the nasal mucosa after endoscopic sinus surgery (ESS) is frequently complicated by scaring and consequently recurrences are encountered. Methods of optimizing results …
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Maintenance of mitochondrial function by astaxanthin protects against bisphenol A-induced kidney toxicity in rats.
PMID: Biomed Pharmacother. 2019 Nov 13 ;121:109629. Epub 2019 Nov 13. PMID: 31733573 Abstract Title: Maintenance of mitochondrial function by astaxanthin protects against bisphenol A-induced kidney toxicity in rats. Abstract: Bisphenol A (BPA), a global environmental pollutant, has been reported to have the potential to induced organs toxicity. This study explored the potential benefits of …
Benzyl isothiocyanate downregulated the expression of virulence factors in staphylococcus aureus.
PMID: Int J Mol Sci. 2019 Oct 31 ;20(21). Epub 2019 Oct 31. PMID: 31683671 Abstract Title: Downregulated Expression of Virulence Factors Induced by Benzyl Isothiocyanate in: A Transcriptomic Analysis. Abstract: () is a common foodborne pathogen that leads to various diseases; therefore, we urgently need to identify different means to control this harmful pathogen …
Perinatal BPA administration in pregnant female mice modulated different cellular and molecular immune components.
n/a PMID: Int J Environ Res Public Health. 2019 Oct 25 ;16(21). Epub 2019 Oct 25. PMID: 31731436 Abstract Title: Environmental Pollution as a Risk Factor in Testicular Tumour Development: Focus on the Interaction between Bisphenol A and the Associated Immune Response. Abstract: Bisphenol A (BPA) is an endocrine disruptor to which animals and humans …